Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1906677 | 0.83 | ALOX15 (0.61) | ALOX15GFERADAM17GAAKDM4E | |
| SCHEMBL21740372 | 0.83 | ALOX15 (0.52) | ALOX15GFERADAM17GAAKDM4E | |
| SCHEMBL11065049 | 0.80 | DRD1 (0.56) | ALOX15GFERADAM17GAAKDM4E | |
| SCHEMBL20161382 | 0.79 | ALOX15 (0.49) | ALOX15GFERADAM17GAAKDM4E | |
| SCHEMBL9247198 | 0.79 | KMT2A (0.63) | GAAKDM4ELMNAPOLBMAPT | |
| SCHEMBL753615 | 0.78 | MAPT (0.70) | ALOX15GFERADAM17GAAKDM4E | |
| SCHEMBL7984136 | 0.78 | ALOX15 (0.56) | ALOX15GFERADAM17GAAKDM4E | |
| SCHEMBL7042503 | 0.77 | ALOX15 (0.66) | ALOX15GFERADAM17KDM4EATM | |
| SCHEMBL2791684 | 0.77 | ALOX15 (0.66) | ALOX15GFERADAM17KDM4EATM | |
| SCHEMBL16959762 | 0.77 | ALOX15 (0.37) | ALOX15GFERADAM17GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0116914-A1 | Preparation of optically-active alpha-substituted carboxylic esters and acids | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-08-29 | — | — | EP | disclosed |