Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | GSR | P00390 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MGAM | O43451 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11096084 | 1.00 | LMNA (0.44) | LMNAL3MBTL1TDP1PDE4AGSR | |
| SCHEMBL11099297 | 1.00 | LMNA (0.44) | LMNAL3MBTL1TDP1PDE4AGSR | |
| SCHEMBL11021827 | 0.85 | LMNA (0.38) | LMNAL3MBTL1TDP1PDE4AGSR | |
| SCHEMBL1147572 | 0.80 | GSR (0.45) | TDP1GSR | |
| SCHEMBL27436736 | 0.80 | TDP1 (0.48) | LMNAL3MBTL1TDP1PDE4AGSR | |
| SCHEMBL27831039 | 0.80 | TDP1 (0.48) | LMNAL3MBTL1TDP1PDE4AGSR | |
| SCHEMBL27487804 | 0.78 | TDP1 (0.46) | LMNAL3MBTL1TDP1PDE4AGSR | |
| SCHEMBL1460202 | 0.76 | LMNA (0.39) | LMNAL3MBTL1TDP1PDE4AGSR | |
| SCHEMBL29085542 | 0.75 | GSR (0.32) | LMNAL3MBTL1TDP1GSR | |
| Mannitol SCHEMBL10952803 | 0.75 | LMNA (0.61) | LMNAL3MBTL1TDP1PDE4AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0044940-B1 | AMINO-DESOXY-1.4;3.6-DIANHYDRO-HEXITE NITRATES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS | Dr. Willmar Schwabe GmbH & Co. (DE) | 1984-09-19 | — | — | EP | claimed |