Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.72 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.72 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.72 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.72 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.72 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.72 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.72 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.72 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.72 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.72 |
| ▸ | MEN1 | O00255 | 1/20 | 0.72 |
| ▸ | XBP1 | P17861 | 1/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.72 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.72 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.72 |
| ▸ | EGFR | P00533 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27713482 | 0.87 | LMNA (0.68) | LMNASLC6A2SLC6A4OPRM1HIF1A | |
| SCHEMBL8644590 | 0.87 | LMNA (0.68) | LMNASLC6A2SLC6A4OPRM1HIF1A | |
| SCHEMBL16784192 | 0.87 | LMNA (0.68) | LMNASLC6A2SLC6A4OPRM1HIF1A | |
| Hydrochloric Acid SCHEMBL4924515 | 0.86 | LMNA (0.66) | LMNASLC6A2SLC6A4OPRM1HIF1A | |
| Hydrochloric Acid SCHEMBL4931174 | 0.86 | LMNA (0.66) | LMNASLC6A2SLC6A4OPRM1HIF1A | |
| SCHEMBL4382670 | 0.85 | LMNA (0.65) | LMNASLC6A2SLC6A4OPRM1HIF1A | |
| SCHEMBL11098346 | 0.85 | LMNA (0.65) | LMNASLC6A2SLC6A4OPRM1HIF1A | |
| SCHEMBL11099420 | 0.85 | LMNA (0.65) | LMNASLC6A2SLC6A4OPRM1HIF1A | |
| SCHEMBL11457910 | 0.85 | SLC6A4 (0.78) | LMNASLC6A2SLC6A4OPRM1HIF1A | |
| SCHEMBL18590346 | 0.85 | LMNA (0.65) | LMNASLC6A2SLC6A4OPRM1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4474977-A | CARDIOVASCULAR DIORDERS, ANTISPASMODIC AGENTS | CONTINENTAL PHARMA S.A. (BE) | 1984-10-02 | — | — | US | disclosed |