Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TTR | P02766 | 2/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11357935 | 0.90 | RAB9A (0.48) | MAOBRAB9ANPC1RXFP1KDM4E | |
| SCHEMBL11102407 | 0.90 | MAOB (0.54) | MAOBRAB9ANPC1RXFP1KDM4E | |
| SCHEMBL11108156 | 0.89 | MAOB (0.56) | MAOBRAB9ANPC1RXFP1KDM4E | |
| SCHEMBL11358593 | 0.88 | MAOB (0.52) | MAOBRAB9ANPC1RXFP1KDM4E | |
| SCHEMBL11106960 | 0.88 | RAB9A (0.59) | MAOBRAB9ANPC1RXFP1KDM4E | |
| SCHEMBL11102213 | 0.87 | RAB9A (0.46) | MAOBRAB9ANPC1RXFP1KDM4E | |
| SCHEMBL11387615 | 0.86 | MAOB (0.50) | MAOBRAB9ANPC1RXFP1KDM4E | |
| SCHEMBL11387611 | 0.86 | MAOB (0.49) | MAOBRAB9ANPC1RXFP1KDM4E | |
| SCHEMBL11356523 | 0.80 | MAOB (0.55) | MAOBRAB9ANPC1RXFP1KDM4E | |
| SCHEMBL10823671 | 0.79 | RAB9A (0.58) | MAOBRAB9ANPC1RXFP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0026675-B1 | 1-AZAXANTHONE-3-CARBOXYLIC ACIDS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Takeda Chemical Industries, Ltd. (JP) | 1984-03-14 | — | — | EP | disclosed |
| US-4302463-A | ANTIALLERGENS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-11-24 | — | — | US | disclosed |