Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11096337 | 1.00 | KMT2A (0.34) | KMT2AP2RX7MEN1HSP90AA1POLB | |
| SCHEMBL11094911 | 0.88 | KMT2A (0.36) | KMT2AP2RX7MEN1HSP90AA1POLB | |
| SCHEMBL10688678 | 0.85 | RAB9A (0.40) | KMT2AP2RX7MEN1HSP90AA1POLB | |
| SCHEMBL11094743 | 0.85 | KMT2A (0.37) | KMT2AP2RX7MEN1HSP90AA1POLB | |
| SCHEMBL11123643 | 0.81 | IDO1 (0.39) | KMT2AP2RX7MEN1HSP90AA1POLB | |
| SCHEMBL11090602 | 0.80 | MGAM (0.35) | KMT2AP2RX7MEN1HSP90AA1POLB | |
| SCHEMBL11097724 | 0.80 | KMT2A (0.33) | KMT2AP2RX7MEN1HSP90AA1POLB | |
| SCHEMBL11097721 | 0.80 | KMT2A (0.33) | KMT2AP2RX7MEN1HSP90AA1POLB | |
| SCHEMBL11094867 | 0.79 | KMT2A (0.38) | KMT2AP2RX7MEN1HSP90AA1POLB | |
| SCHEMBL10918601 | 0.79 | MAPT (0.39) | KMT2AP2RX7MEN1HSP90AA1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0117485-A2 | Pyridine, pyrazine and pyrimidine derivatives and their use as fungicides | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1984-09-05 | — | — | EP | claimed |