Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | PI4KA | P42356 | 1/20 | 0.39 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.39 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | PKM | P14618 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10752633 | 0.78 | CCNB2 (0.40) | TDP1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL7787699 | 0.75 | DYRK1A (0.44) | ALDH1A1KDM4EHSD17B10RAB9ANPC1 | |
| SCHEMBL14762862 | 0.72 | HSD17B10 (0.41) | TDP1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL4493170 | 0.71 | ESR1 (0.45) | TDP1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL31169204 | 0.69 | KDM4E (0.36) | TDP1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL20773930 | 0.67 | CYP2A6 (0.35) | KDM4EHSD17B10DYRK1ANFKB1KMO | |
| SCHEMBL30731377 | 0.67 | DYRK1A (0.30) | DYRK1A | |
| SCHEMBL9307675 | 0.66 | ESR1 (0.44) | TDP1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL6652020 | 0.65 | ALDH1A1 (0.56) | TDP1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL30731375 | 0.65 | MAP4K4 (0.34) | TDP1ALDH1A1HPGDKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0033612-B1 | PYRANO DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND ANTIHYPERTENSIVE COMPOSITIONS CONTAINING THEM | BEECHAM GROUP PLC (GB) | 1984-04-11 | — | — | EP | claimed |
| WO-2024240268-A1 | CEREBELLAR PROTEIN E3 UBIQUITIN LIGASE INHIBITOR AND CHIMERIC COMPOUND TARGETING PROTEIN DEGRADATION | 甘李药业股份有限公司 | 2024-11-28 | — | — | WO | disclosed |