Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 13/20 | 0.62 |
| ▸ | TTR | P02766 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.62 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.62 |
| ▸ | PPARG | P37231 | 1/20 | 0.62 |
| ▸ | HTR2B | P41595 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.62 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.62 |
| ▸ | LTB4R | Q15722 | 4/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11098896 | 0.87 | PPARA (0.58) | PPARATTRCYP1A2CYP2C8CHRM1 | |
| SCHEMBL11091256 | 0.84 | PPARA (0.46) | PPARATTRCYP1A2CYP2C8CHRM1 | |
| SCHEMBL11087920 | 0.82 | PPARA (0.59) | PPARATTRCYP1A2CYP2C8CHRM1 | |
| SCHEMBL28137763 | 0.82 | KDM4E (0.56) | PPARATTRCYP1A2CYP2C8CHRM1 | |
| SCHEMBL10474995 | 0.81 | PPARA (0.58) | PPARATTRCYP1A2CYP2C8CHRM1 | |
| SCHEMBL28138301 | 0.80 | PPARA (0.57) | PPARATTRCYP1A2CYP2C8CHRM1 | |
| SCHEMBL11090319 | 0.80 | PPARA (0.75) | PPARATTRCYP1A2CYP2C8CHRM1 | |
| SCHEMBL11091339 | 0.80 | PPARA (0.56) | PPARATTRCYP1A2CYP2C8CHRM1 | |
| SCHEMBL11088495 | 0.79 | PPARA (0.72) | PPARATTRCYP1A2CYP2C8CHRM1 | |
| SCHEMBL6026957 | 0.79 | PPARA (0.50) | PPARATTRCYP1A2CYP2C8CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0032063-B1 | NOVEL SUBSTITUTED ARYLENE COMPOUNDS AND PROCESSES FOR THEIR PRODUCTION | WARNER-LAMBERT COMPANY (US) | 1984-03-14 | — | — | EP | claimed |