Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 13/20 | 0.50 |
| ▸ | TTR | P02766 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.50 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.41 |
| ▸ | RELA | Q04206 | 3/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11208139 | 0.85 | CYP4F2 (0.42) | PPARATTRCYP1A2CYP2C8CHRM1 | |
| SCHEMBL1947029 | 0.82 | NFKB1 (0.53) | CYP1A2CYP2C8CYP2C9SMN1; SMN2TDP1 | |
| SCHEMBL6026502 | 0.79 | TSHR (0.44) | PPARATSHRSMN1; SMN2TDP1LTB4R | |
| SCHEMBL15357251 | 0.79 | GAA (0.56) | CYP1A2CYP2C8CYP2C9HTR2BSMN1; SMN2 | |
| SCHEMBL11096802 | 0.79 | PPARA (0.62) | PPARATTRCYP1A2CYP2C8CHRM1 | |
| SCHEMBL11098896 | 0.79 | PPARA (0.58) | PPARATTRCYP1A2CYP2C8CHRM1 | |
| Velaresol SCHEMBL61907 | 0.78 | PPARA (0.44) | PPARATSHRSMN1; SMN2LTB4RJAK2 | |
| SCHEMBL11382179 | 0.77 | GAA (0.51) | CYP1A2CYP2C8CYP2C9HTR2BSMN1; SMN2 | |
| SCHEMBL15349839 | 0.77 | LMNA (0.47) | CYP1A2CYP2C8CYP2C9SMN1; SMN2TDP1 | |
| SCHEMBL6026140 | 0.77 | LTB4R (0.45) | PPARASMN1; SMN2LTB4RJAK2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110872228-A | Compound of substituted phenol ether and intermediate and preparation method thereof | 湖北普星特化学试剂有限公司 | 2020-03-10 | — | — | CN | claimed |
| US-7074770-B1 | Method of DNA vaccination | SMITHKLINE BEECHAM CORPORATION (US) | 2006-07-11 | — | — | US | claimed |
| CN-1326358-A | Method of DNA vaccination | GLAXO GROUP LTD (GB) | 2001-12-12 | — | — | CN | claimed |
| EP-1107785-A1 | METHOD OF DNA VACCINATION | GLAXO GROUP LIMITED (GB) | 2001-06-20 | — | — | EP | claimed |
| WO-2000012121-A1 | METHOD OF DNA VACCINATION | GLAXO GROUP LIMITED (GB) | 2000-03-09 | — | — | WO | claimed |
| US-4410537-A | 3-HYDROXY-2-FORMYLPHENOXYPENTANOIC ACID DERIVATIVES | BURROUGHTS WELLCOME CO. (US) | 1983-10-18 | — | — | US | claimed |
| EP-0022229-B1 | SUBSTITUTED PHENOL ETHERS, THEIR PREPARATION, INTERMEDIATES THEREFOR, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THE PREPARATION THEREOF | THE WELLCOME FOUNDATION LIMITED (GB) | 1982-12-08 | — | — | EP | claimed |
| EP-0022229-A1 | Substituted phenol ethers, their preparation, intermediates therefor, pharmaceutical compositions containing them and the preparation thereof | THE WELLCOME FOUNDATION LIMITED (GB) | 1981-01-14 | — | — | EP | claimed |
| CN-110872228-A | Compound of substituted phenol ether and intermediate and preparation method thereof | 湖北普星特化学试剂有限公司 | 2020-03-10 | — | — | CN | disclosed |
| US-7074770-B1 | Method of DNA vaccination | SMITHKLINE BEECHAM CORPORATION (US) | 2006-07-11 | — | — | US | disclosed |
| CN-1326358-A | Method of DNA vaccination | GLAXO GROUP LTD (GB) | 2001-12-12 | — | — | CN | disclosed |
| EP-1107785-A1 | METHOD OF DNA VACCINATION | GLAXO GROUP LIMITED (GB) | 2001-06-20 | — | — | EP | disclosed |
| WO-2000012121-A1 | METHOD OF DNA VACCINATION | GLAXO GROUP LIMITED (GB) | 2000-03-09 | — | — | WO | disclosed |
| EP-0614357-A1 | IMMUNOPOTENTIATORY AGENTS | THE WELLCOME FOUNDATION LIMITED (GB) | 1994-09-14 | — | — | EP | disclosed |
| WO-1994007479-A2 | IMMUNOPOTENTIATORY AGENTS | THE WELLCOME FOUNDATION LIMITED (GB) | 1994-04-14 | — | — | WO | disclosed |
| US-4410537-A | 3-HYDROXY-2-FORMYLPHENOXYPENTANOIC ACID DERIVATIVES | BURROUGHTS WELLCOME CO. (US) | 1983-10-18 | — | — | US | disclosed |
| EP-0022229-B1 | SUBSTITUTED PHENOL ETHERS, THEIR PREPARATION, INTERMEDIATES THEREFOR, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THE PREPARATION THEREOF | THE WELLCOME FOUNDATION LIMITED (GB) | 1982-12-08 | — | — | EP | disclosed |
| EP-0022229-A1 | Substituted phenol ethers, their preparation, intermediates therefor, pharmaceutical compositions containing them and the preparation thereof | THE WELLCOME FOUNDATION LIMITED (GB) | 1981-01-14 | — | — | EP | disclosed |