Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | FDPS | P14324 | 6/20 | 0.48 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.48 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 3/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22430399 | 0.83 | TDP1 (0.58) | TDP1L3MBTL1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL20366346 | 0.81 | TDP1 (0.59) | TDP1L3MBTL1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL27498473 | 0.80 | TDP1 (0.58) | TDP1L3MBTL1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL14779954 | 0.79 | GAA (0.44) | CYP1A2CYP2C9CYP2C19MMP1MMP9 | |
| SCHEMBL25380936 | 0.75 | TDP1 (0.96) | TDP1L3MBTL1TRPV1 | |
| SCHEMBL25381701 | 0.75 | TDP1 (0.96) | TDP1L3MBTL1TRPV1 | |
| SCHEMBL6114977 | 0.75 | TDP1 (0.96) | TDP1L3MBTL1TRPV1 | |
| SCHEMBL25381172 | 0.75 | TDP1 (0.96) | TDP1L3MBTL1TRPV1 | |
| SCHEMBL6114843 | 0.75 | TDP1 (0.96) | TDP1L3MBTL1TRPV1 | |
| SCHEMBL6115279 | 0.75 | TDP1 (0.96) | TDP1L3MBTL1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0109299-A2 | 1,1-Disubstituted-2-heterocyclic ethanol derivatives | ELI LILLY AND COMPANY (US) | 1984-05-23 | — | — | EP | disclosed |