SCHEMBL11097009

SCHEMBL11097009

C=CC(=O)OOCCCCC

nearest known ligand 0.57

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 9/20 0.57
HPGD P15428 1/20 0.57
ALDH1A1 P00352 3/20 0.47
CYP3A4 P08684 1/20 0.47
THRB P10828 2/20 0.44
HCAR2 Q8TDS4 2/20 0.43
ATM Q13315 1/20 0.41
ZDHHC20 Q5W0Z9 2/20 0.40
ZDHHC2 Q9UIJ5 1/20 0.40
THRA P10827 1/20 0.40
NAAA Q02083 1/20 0.39
CES2 O00748 1/20 0.38
TP53 P04637 2/20 0.38
HIF1A Q16665 2/20 0.38
HSD17B10 Q99714 1/20 0.38
EPHX1 P07099 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28203312 0.98 TSHR (0.55) TSHRHPGDALDH1A1CYP3A4THRB
SCHEMBL31520137 0.98 TSHR (0.55) TSHRHPGDALDH1A1CYP3A4THRB
SCHEMBL28228300 0.98 TSHR (0.55) TSHRHPGDALDH1A1CYP3A4THRB
SCHEMBL28023258 0.98 TSHR (0.55) TSHRHPGDALDH1A1CYP3A4THRB
SCHEMBL27650354 0.94 TSHR (0.64) TSHRHPGDALDH1A1CYP3A4THRB
SCHEMBL3181990 0.85
SCHEMBL9579502 0.82 HCAR2 (0.56) TSHRHPGDHCAR2ATMNAAA
SCHEMBL3220127 0.82 TSHR (0.72) TSHRHPGDALDH1A1CYP3A4THRB
SCHEMBL27685045 0.79 TSHR (0.50) TSHRHPGDALDH1A1CYP3A4THRB
SCHEMBL33111 0.79 TSHR (0.88) TSHRHPGDALDH1A1CYP3A4THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109369600-B Synthesis method of 2-substituted methylene aromatic ring benzopyran compound 河南师范大学 2021-08-03 CN claimed
CN-1427771-A In situ microencapsulated adhesive APPLETON PAPER INC (US) 2003-07-02 CN claimed
CN-116323726-A Active energy ray-curable composition, cured product, lens, and camera module DIC株式会社 2023-06-23 CN disclosed
CN-109369600-B Synthesis method of 2-substituted methylene aromatic ring benzopyran compound 河南师范大学 2021-08-03 CN disclosed
CN-109369600-B Synthesis method of 2-substituted methylene aromatic ring benzopyran compound 河南师范大学 2021-08-03 CN disclosed
US-20160276491-A1 Thin Film Transistor, Array Substrate and Display Device BOE TECHNOLOGY GROUP CO., LTD. (CN) 2016-09-22 US disclosed
CN-102482187-B Method for producing bioresourced acrylic acid from glycerol ARKEMA FRANCE 2015-05-20 CN disclosed
CN-102300881-B Method for producing random radical copolymers and corresponding active ingredient compositions obtainable therefrom BASF SE 2015-04-08 CN disclosed
CN-102482187-A Method for producing a bio-derived acrylic acid from glycerol ARKEMA FRANCE 2012-05-30 CN disclosed
CN-102300881-A Method For Producing Random Radical Copolymers And Corresponding Active Ingredient Compositions Obtainable Therefrom 2011-12-28 CN disclosed
CN-1427771-A In situ microencapsulated adhesive APPLETON PAPER INC (US) 2003-07-02 CN disclosed
US-4440919-A CROSSLINKED WITH RESONANCE FREE DI(ALKENE TERTIARY AMINE) CYCLIC COMPOUNDS BAUSCH & LOMB INCORPORATED (US) 1984-04-03 US disclosed
US-4436887-A CONTACT LENSES, OXYGEN PERMEABILITY BAUSCH & LOMB INCORPORATED (US) 1984-03-13 US disclosed
EP-0079721-A2 N-vinyl lactam-based biomedical devices and process for preparation thereof BAUSCH & LOMB INCORPORATED (US) 1983-05-25 EP disclosed
EP-0079720-A2 Low n-vinyl lactam content-based biomedical devices and process for preparation thereof BAUSCH & LOMB INCORPORATED (US) 1983-05-25 EP disclosed