SCHEMBL11097010

SCHEMBL11097010

CCCN1CNC(=O)NC1=O

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.33
MEN1 O00255 1/20 0.31
THRB P10828 1/20 0.31
POLB P06746 1/20 0.31
ALOX12 P18054 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
TAAR1 Q96RJ0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11190250 0.88 KMT2A (0.42) KMT2AMEN1SMN1; SMN2
SCHEMBL11097087 0.83 CRBN (0.34) KMT2A
SCHEMBL11104438 0.82 KMT2A (0.38) KMT2AL3MBTL1MEN1THRBALOX12
SCHEMBL11101804 0.82 KMT2A (0.33) KMT2AL3MBTL1
SCHEMBL11104742 0.75 KMT2A (0.32) KMT2A
SCHEMBL11096238 0.73 KMT2A (0.35) KMT2A
SCHEMBL11099386 0.73 KMT2A (0.31) KMT2A
SCHEMBL268470 0.71 KMT2A (0.61) KMT2AL3MBTL1MEN1THRBPOLB
SCHEMBL28883614 0.71 CYP3A4 (0.38) KMT2AL3MBTL1MEN1POLB
SCHEMBL3068428 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4477442-A PENTOFURANOSYL-5,6-DIHYDROTRIAZINES IN TREATMENT OF VIRAL DISEASES THE UPJOHN COMPANY (US) 1984-10-16 US disclosed
US-4423212-A Nucleosides and process THE UPJOHN COMPANY (US) 1983-12-27 US disclosed
US-4239753-A Composition of matter and process THE UPJOHN COMPANY (US) 1980-12-16 US disclosed
US-4171431-A Nucleosides and process THE UPJOHN COMPANY (US) 1979-10-16 US disclosed