SCHEMBL3068428

SCHEMBL3068428

CN1CNC(=O)NC1=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL821227 0.80
SCHEMBL11102459 0.78
SCHEMBL11104026 0.78
SCHEMBL3499897 0.75
SCHEMBL17704772 0.70
SCHEMBL11097010 0.70 KMT2A (0.36)
SCHEMBL11102000 0.69 MIF (0.33)
SCHEMBL3193395 0.69
SCHEMBL11097087 0.69 CRBN (0.34)
SCHEMBL11100095 0.69 MAPT (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9334299-B2 Water-soluble camptothecin derivative, pharmaceutical composition and use thereof HUNAN FANGSHENGHUAMEI MEDICAL TECH. CO. LTD. (CN) 2016-05-10 US claimed
CN-102153607-B Water soluble camptothecin derivative and medicinal composition containing same HUNAN FANGSHENG HUAMEI MEDICAL TECHNOLOGY CO LTD 2015-07-15 CN claimed
US-20140155336-A1 WATER-SOLUBLE CAMPTOTHECIN DERIVATIVE, PHARMACEUTICAL COMPOSITION AND USE THEREOF HUNAN FANGSHENGHUAMEI MEDICAL TECH. CO. LTD. (CN) 2014-06-05 US claimed
CN-102153607-A Water soluble camptothecin derivative and medicinal composition containing same HUNAN FANGSHENG HUAMEI MEDICAL TECHNOLOGY CO LTD 2011-08-17 CN claimed
US-20250313838-A1 NUCLEIC ACID FOR TRANSFECTION AGC Inc. (JP) 2025-10-09 US disclosed
EP-4585684-A1 NUCLEIC ACID FOR TRANSFECTION AGC INC. (JP) 2025-07-16 EP disclosed
CN-119731318-A Nucleic acid for transfection AGC株式会社 2025-03-28 CN disclosed
CN-119654411-A Method for producing oligonucleotide 味之素株式会社 2025-03-18 CN disclosed
CN-119487210-A Repeated short read sequencing within a cell sample 元素生物科学公司 2025-02-18 CN disclosed
US-20240009224-A1 ACYCLIC THREONINOL NUCLEIC ACID THE UNIVERSITY OF TOKYO (JP) 2024-01-11 US disclosed
EP-4303303-A1 ACYCLIC THREONINOL NUCLEIC ACID The University of Tokyo (JP) 2024-01-10 EP disclosed
CN-116917476-A Acyclic threitol nucleic acids 国立大学法人东京大学 2023-10-20 CN disclosed
US-5384251-A Culture of Bacillus to produce nucleoside phosphorylase YAMASA SHOYU KABUSHIKI KAISHA (JP) 1995-01-24 US disclosed
US-5258301-A Nucleoside phosphorylase from Bacillus YAMASA SHOYU KABUSHIKI KAISHA (JP) 1993-11-02 US disclosed
EP-0411158-A1 Process for producing nucleosides by using phosphorylases obtainable from Bacillus stearothermophilus Yamasa Shoyu Kabushiki Kaisha (Yamasa Corporation) (JP) 1991-02-06 EP disclosed
EP-0233493-A2 Process for producing ribonucleosides Yamasa Shoyu Kabushiki Kaisha (JP) 1987-08-26 EP disclosed
US-4477442-A PENTOFURANOSYL-5,6-DIHYDROTRIAZINES IN TREATMENT OF VIRAL DISEASES THE UPJOHN COMPANY (US) 1984-10-16 US disclosed
US-4423212-A Nucleosides and process THE UPJOHN COMPANY (US) 1983-12-27 US disclosed
US-4239753-A Composition of matter and process THE UPJOHN COMPANY (US) 1980-12-16 US disclosed
US-4171431-A Nucleosides and process THE UPJOHN COMPANY (US) 1979-10-16 US disclosed