Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR3 | O60755 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | THRB | P10828 | 1/20 | 0.64 |
| ▸ | PDE3B | Q13370 | 16/20 | 0.63 |
| ▸ | PDE3A | Q14432 | 16/20 | 0.63 |
| ▸ | PDE4A | P27815 | 3/20 | 0.60 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.60 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.60 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.60 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2583128 | 0.90 | GALR3 (0.66) | GALR3MAPTTHRBPDE3BPDE3A | |
| SCHEMBL992766 | 0.87 | GALR3 (0.72) | GALR3MAPTTHRBPDE3BPDE3A | |
| SCHEMBL9688046 | 0.86 | PDE3B (0.63) | GALR3MAPTTHRBPDE3BPDE3A | |
| SCHEMBL9686024 | 0.85 | PDE3B (0.78) | GALR3MAPTTHRBPDE3BPDE3A | |
| SCHEMBL2842077 | 0.85 | PDE3B (0.62) | GALR3MAPTTHRBPDE3BPDE3A | |
| SCHEMBL21225874 | 0.84 | GALR3 (0.69) | GALR3MAPTTHRBPDE3BPDE3A | |
| SCHEMBL30100309 | 0.84 | GALR3 (0.69) | GALR3MAPTTHRBPDE3BPDE3A | |
| SCHEMBL31117110 | 0.83 | GALR3 (0.67) | GALR3MAPTTHRBPDE3BPDE3A | |
| SCHEMBL16157197 | 0.83 | GALR3 (0.67) | GALR3MAPTTHRBPDE3BPDE3A | |
| SCHEMBL7267644 | 0.83 | PDE3B (0.80) | GALR3MAPTTHRBPDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0034743-B1 | BENZOXAZOLES, THEIR PREPARATION AND THEIR USE AS MEDICINES | Dr. Karl Thomae GmbH (DE) | 1984-05-30 | — | — | EP | disclosed |
| EP-0034743-A1 | Benzoxazoles, their preparation and their use as medicines | Dr. Karl Thomae GmbH (DE) | 1981-09-02 | — | — | EP | disclosed |