Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9647321 | 0.90 | MEN1 (0.49) | KMT2AMEN1NPC1MMP8SMN1; SMN2 | |
| SCHEMBL29747036 | 0.82 | KMT2A (0.50) | KMT2AMEN1NPC1SMN1; SMN2RAB9A | |
| Ethylene SCHEMBL10550791 | 0.80 | KMT2A (0.56) | KMT2AMEN1NPC1SMN1; SMN2RAB9A | |
| SCHEMBL124577 | 0.80 | KMT2A (0.59) | KMT2AMEN1NPC1SMN1; SMN2RAB9A | |
| SCHEMBL286 | 0.79 | SLC6A3 (0.51) | KMT2AMEN1SMN1; SMN2RAB9ACA12 | |
| SCHEMBL17433663 | 0.78 | KMT2A (0.57) | KMT2AMEN1NPC1SMN1; SMN2RAB9A | |
| SCHEMBL17433560 | 0.78 | KMT2A (0.57) | KMT2AMEN1NPC1SMN1; SMN2RAB9A | |
| SCHEMBL31439645 | 0.78 | KMT2A (0.57) | KMT2AMEN1NPC1SMN1; SMN2RAB9A | |
| SCHEMBL17433641 | 0.78 | KMT2A (0.57) | KMT2AMEN1NPC1SMN1; SMN2RAB9A | |
| SCHEMBL28792148 | 0.78 | KMT2A (0.57) | KMT2AMEN1NPC1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0104959-A1 | 4-Quinolone derivatives | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1984-04-04 | — | — | EP | disclosed |