SCHEMBL11097133

SCHEMBL11097133

CC(Cc1ccc(Cl)cc1)C(O)(c1ccc(Cl)cc1)C(C)n1ccnc1

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 12/20 0.44
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
CYP2A6 P11509 1/20 0.40
CYP11B1 P15538 1/20 0.40
CYP11B2 P19099 1/20 0.40
CYP2B6 P20813 1/20 0.40
CYP3A4 P08684 1/20 0.40
ADORA3 P0DMS8 1/20 0.40
CHRM1 P11229 1/20 0.40
SLC6A2 P23975 1/20 0.40
SLC6A4 P31645 1/20 0.40
ADRA1A P35348 1/20 0.40
SLC6A3 Q01959 1/20 0.40
CYP24A1 Q07973 1/20 0.39
TBXA2R P21731 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9198411 0.82 CYP19A1 (0.52) CYP19A1MEN1KMT2ACYP3A4ADORA3
SCHEMBL9196055 0.82 CYP19A1 (0.52) CYP19A1MEN1KMT2ACYP3A4ADORA3
SCHEMBL9996089 0.74 MEN1 (0.49) CYP19A1MEN1KMT2ACYP2A6CYP11B1
Hydrochloric Acid SCHEMBL412437 0.73 MEN1 (0.48) CYP19A1MEN1KMT2ACYP2A6CYP11B1
SCHEMBL10247377 0.70 CYP24A1 (0.54) CYP19A1MEN1KMT2ACYP2A6CYP11B1
SCHEMBL9199407 0.70 CYP19A1 (0.51) CYP19A1CYP11B1CYP11B2CYP24A1
SCHEMBL9199400 0.70 CYP19A1 (0.51) CYP19A1CYP11B1CYP11B2CYP24A1
Hydrochloric Acid SCHEMBL1776701 0.69 CYP24A1 (0.53) CYP19A1MEN1KMT2ACYP2A6CYP11B1
SCHEMBL9021041 0.69 CYP19A1 (0.43) CYP19A1MEN1KMT2ACYP2A6CYP11B1
SCHEMBL8447279 0.68 CYP19A1 (0.47) CYP19A1MEN1KMT2ACYP2A6CYP11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0111234-A2 Fungicidal agents, their preparation and use BAYER AG (DE) 1984-06-20 EP disclosed