Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | EDNRA | P25101 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30950298 | 0.98 | ALDH1A1 (0.44) | ALDH1A1TDP1HSD17B10L3MBTL1RXFP1 | |
| SCHEMBL4439 | 0.98 | ALDH1A1 (0.44) | ALDH1A1TDP1HSD17B10L3MBTL1RXFP1 | |
| SCHEMBL1584603 | 0.95 | ALDH1A1 (0.42) | ALDH1A1TDP1HSD17B10L3MBTL1RXFP1 | |
| Hydrochloric Acid SCHEMBL28295084 | 0.95 | ALDH1A1 (0.42) | ALDH1A1TDP1HSD17B10L3MBTL1RXFP1 | |
| Water SCHEMBL9476427 | 0.95 | ALDH1A1 (0.42) | ALDH1A1TDP1HSD17B10L3MBTL1RXFP1 | |
| SCHEMBL1584604 | 0.95 | ALDH1A1 (0.48) | ALDH1A1TDP1HSD17B10L3MBTL1RXFP1 | |
| SCHEMBL10818751 | 0.87 | ALDH1A1 (0.64) | ALDH1A1TDP1HSD17B10L3MBTL1RXFP1 | |
| SCHEMBL28708247 | 0.84 | ALDH1A1 (0.48) | ALDH1A1TDP1HSD17B10L3MBTL1RXFP1 | |
| Pyridine SCHEMBL7211274 | 0.84 | ALDH1A1 (0.47) | ALDH1A1TDP1HSD17B10L3MBTL1RXFP1 | |
| Benzoic Acid SCHEMBL11351670 | 0.82 | DAO (0.50) | ALDH1A1TDP1L3MBTL1SLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2279254-A1 | NOVEL LIPID FORMULATIONS FOR NUCLEIC ACID DELIVERY | Protiva Biotherapeutics Inc. (CA) | 2011-02-02 | — | — | EP | disclosed |
| WO-2009127060-A1 | NOVEL LIPID FORMULATIONS FOR NUCLEIC ACID DELIVERY | PROTIVA BIOTHERAPEUTICS, INC. (CA) | 2009-10-22 | — | — | WO | disclosed |