⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11576404 | 0.92 | FDPS (0.46) | — | |
| SCHEMBL11102665 | 0.90 | SMPD1 (0.48) | — | |
| SCHEMBL11182482 | 0.90 | SMPD1 (0.48) | — | |
| SCHEMBL11234308 | 0.90 | SMPD1 (0.48) | — | |
| SCHEMBL11235739 | 0.90 | SMPD1 (0.48) | — | |
| SCHEMBL10791301 | 0.85 | CYP2D6 (0.39) | — | |
| SCHEMBL372172 | 0.85 | FDPS (0.44) | — | |
| SCHEMBL1669837 | 0.82 | CYP2D6 (0.37) | — | |
| SCHEMBL10909327 | 0.82 | — | — | |
| Ammonia Solution, Strong SCHEMBL28112649 | 0.82 | FDPS (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210340141-A1 | TLR8 AGONIST | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2021-11-04 | — | — | US | disclosed |
| EP-3875451-A1 | TLR8 AGONIST | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2021-09-08 | — | — | EP | disclosed |
| EP-0001284-B1 | UV-LIGHT STABILIZED COMPOSITIONS CONTAINING SUBSTITUTED 2-KETO-1,4-DIAZACYCLOALKANES | The B.F. GOODRICH Company (US) | 1984-05-23 | — | — | EP | disclosed |
| EP-0001559-B1 | SYNTHESIS OF 2-KETO-1,4-DIAZACYCLOALKANES | The B.F. GOODRICH Company (US) | 1982-01-13 | — | — | EP | disclosed |
| EP-0024337-A1 | Synthesis of 2-keto-1,4-diazacycloalkanes | The B.F. GOODRICH Company (US) | 1981-03-04 | — | — | EP | disclosed |
| EP-0001559-A2 | Synthesis of 2-keto-1,4-diazacycloalkanes | The B.F. GOODRICH Company (US) | 1979-05-02 | — | — | EP | disclosed |
| EP-0001284-A1 | UV-light stabilized compositions containing substituted 2-keto-1,4-diazacycloalkanes | The B.F. GOODRICH Company (US) | 1979-04-04 | — | — | EP | disclosed |