Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31456124 | 0.93 | TDP1 (0.39) | TDP1HTTALDH1A1HPGDS1PR1 | |
| SCHEMBL20590031 | 0.76 | — | — | |
| SCHEMBL4257766 | 0.76 | S1PR1 (0.57) | TDP1HTTALDH1A1HPGDS1PR1 | |
| SCHEMBL4138249 | 0.75 | NPC1 (0.42) | ALDH1A1HPGDS1PR1NPSR1POLB | |
| SCHEMBL20856090 | 0.74 | S1PR1 (0.47) | TDP1HTTALDH1A1HPGDS1PR1 | |
| Fluoride SCHEMBL20513066 | 0.73 | TDP1 (0.58) | TDP1HTTALDH1A1HPGDMEN1 | |
| Fluoride SCHEMBL21331933 | 0.73 | TDP1 (0.58) | TDP1HTTALDH1A1HPGDMEN1 | |
| Potassium SCHEMBL31706685 | 0.73 | S1PR1 (0.46) | TDP1HTTALDH1A1HPGDS1PR1 | |
| SCHEMBL38726 | 0.71 | TDP1 (0.61) | TDP1ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL11904537 | 0.71 | TDP1 (0.61) | TDP1ALDH1A1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0120613-A1 | Penem derivatives and precursors | BEECHAM GROUP PLC (GB) | 1984-10-03 | — | — | EP | disclosed |