Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21222589 | 0.78 | CES2 (0.58) | NPC1TSHRMAPK1POLBALDH1A1 | |
| SCHEMBL11097613 | 0.75 | TDP1 (0.41) | POLBALDH1A1MAPTHPGDNPSR1 | |
| SCHEMBL510447 | 0.72 | LMNA (0.33) | NPC1TSHRPOLBALDH1A1LMNA | |
| SCHEMBL3624444 | 0.72 | NPC1 (0.58) | NPC1TSHRMAPK1ALDH1A1MAPT | |
| SCHEMBL752897 | 0.70 | MAOA (0.51) | NPC1TSHRMAPK1POLBALDH1A1 | |
| SCHEMBL31456124 | 0.69 | TDP1 (0.39) | POLBALDH1A1LMNAKDM4EHPGD | |
| SCHEMBL4128859 | 0.68 | KDM4E (0.35) | KDM4E | |
| SCHEMBL20590031 | 0.68 | — | — | |
| SCHEMBL2958453 | 0.67 | LMNA (0.64) | NPC1TSHRMAPK1POLBALDH1A1 | |
| SCHEMBL21230335 | 0.66 | LMNA (0.42) | NPC1TSHRMAPK1POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090247772-A1 | Method for the Preparation of Escitalopram | H. LUNDBECK A/S (DK) | 2009-10-01 | — | — | US | claimed |
| US-20090247772-A1 | Method for the Preparation of Escitalopram | H. LUNDBECK A/S (DK) | 2009-10-01 | — | — | US | disclosed |
| US-20090247772-A1 | Method for the Preparation of Escitalopram | H. LUNDBECK A/S (DK) | 2009-10-01 | — | — | US | disclosed |
| US-20090247772-A1 | Method for the Preparation of Escitalopram | H. LUNDBECK A/S (DK) | 2009-10-01 | — | — | US | disclosed |
| WO-2007054105-A2 | METHOD FOR THE PREPARATION OF ESCITALOPRAM | H. LUNDBECK A/S (DK) | 2007-05-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247772-A1 | Method for the Preparation of Escitalopram | SLC6A4, SLC6A2, SLC6A3 | NPC1 1193/4885TSHR 3730/4885MAPK1 3767/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.