Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 6/20 | 0.70 |
| ▸ | ATP4B | P51164 | 6/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.70 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | BLM | P54132 | 1/20 | 0.70 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.70 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.49 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.49 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.49 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.49 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.49 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1815961 | 0.82 | ATP4A (1.00) | ATP4AATP4BCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8563527 | 0.81 | CYP1A2 (0.62) | ATP4AATP4BCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11187457 | 0.81 | CYP3A4 (0.47) | ATP4AATP4BCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL2192635 | 0.81 | ATP4A (0.83) | ATP4AATP4BCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9746953 | 0.81 | CYP3A4 (0.68) | ATP4AATP4BCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL10646302 | 0.80 | ATP4A (0.70) | ATP4AATP4BCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL2189930 | 0.80 | ATP4A (0.81) | ATP4AATP4BCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL10533472 | 0.80 | ATP4A (0.81) | ATP4AATP4BCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL2189553 | 0.80 | ATP4A (0.73) | ATP4AATP4BCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL2192833 | 0.79 | ATP4A (0.72) | ATP4AATP4BCYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0033094-B1 | IMIDAZO(1,2-A)PYRIDINES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCHERING CORPORATION (US) | 1984-10-10 | — | — | EP | claimed |
| EP-0033094-B1 | IMIDAZO(1,2-A)PYRIDINES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCHERING CORPORATION (US) | 1984-10-10 | — | — | EP | disclosed |
| EP-0033094-A1 | Imidazo(1,2-a)pyridines, processes for their preparation and pharmaceutical compositions containing them | SCHERING CORPORATION (US) | 1981-08-05 | — | — | EP | disclosed |