SCHEMBL11097853

SCHEMBL11097853

Nc1ccc(Cl)c(Cl)c1S(=O)(=O)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.47
TSHR P16473 4/20 0.47
CYP3A4 P08684 3/20 0.47
THRB P10828 2/20 0.47
RECQL P46063 2/20 0.47
HSD17B10 Q99714 2/20 0.47
HPGD P15428 1/20 0.47
ALOX15 P16050 1/20 0.47
CASP1 P29466 1/20 0.47
CYP2C9 P11712 1/20 0.41
CA12 O43570 3/20 0.38
CA1 P00915 3/20 0.38
CA2 P00918 3/20 0.38
CA7 P43166 3/20 0.38
CA9 Q16790 3/20 0.38
CA14 Q9ULX7 3/20 0.38
CA4 P22748 2/20 0.38
CA6 P23280 2/20 0.38
CA5A P35218 2/20 0.38
CA5B Q9Y2D0 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9807310 0.85 ALDH1A1 (0.48) ALDH1A1TSHRCYP3A4THRBRECQL
SCHEMBL5353246 0.81 CA1 (0.48) ALDH1A1TSHRCYP3A4THRBRECQL
SCHEMBL7554123 0.80 ALDH1A1 (0.40) ALDH1A1TSHRCYP3A4THRBRECQL
SCHEMBL4991882 0.80 ALDH1A1 (0.44) ALDH1A1TSHRCYP3A4THRBRECQL
SCHEMBL11006119 0.79 ALDH1A1 (0.38) ALDH1A1TSHRCYP3A4THRBRECQL
SCHEMBL8164868 0.79 ALDH1A1 (0.46) ALDH1A1TSHRCYP3A4THRBRECQL
SCHEMBL27577874 0.78 CYP2C9 (0.37) ALDH1A1TSHRCYP3A4THRBRECQL
SCHEMBL27657206 0.77 CYP2C9 (0.36) ALDH1A1TSHRCYP3A4THRBRECQL
SCHEMBL1955903 0.77 CYP3A4 (0.50) ALDH1A1TSHRCYP3A4THRBRECQL
SCHEMBL9232347 0.76 ALDH1A1 (0.44) ALDH1A1TSHRCYP3A4THRBRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4467088-A USEFULL IN PREPARATION OF DYES CIBA-GEIGY CORPORATION (US) 1984-08-21 US disclosed
US-4014866-A FOR SURFACE COATINGS, PRINTING INKS AND RESINS BASF AKTIENGESELLSCHAFT (DT) 1977-03-29 US disclosed