Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15187940 | 1.00 | SHBG (0.42) | SHBGTP53KDM4EGMNNLMNA | |
| SCHEMBL10077547 | 0.81 | SHBG (0.56) | SHBGTP53KDM4EGMNNLMNA | |
| SCHEMBL11797019 | 0.81 | TP53 (0.41) | SHBGTP53KDM4EGMNNLMNA | |
| SCHEMBL15660950 | 0.81 | — | — | |
| SCHEMBL17060908 | 0.77 | SHBG (0.44) | SHBGTP53KDM4EGMNNLMNA | |
| SCHEMBL295412 | 0.77 | SHBG (0.44) | SHBGTP53KDM4EGMNNLMNA | |
| SCHEMBL9819929 | 0.77 | SHBG (0.44) | SHBGTP53KDM4EGMNNLMNA | |
| SCHEMBL9921613 | 0.77 | SHBG (0.44) | SHBGTP53KDM4EGMNNLMNA | |
| SCHEMBL9898281 | 0.77 | SHBG (0.44) | SHBGTP53KDM4EGMNNLMNA | |
| SCHEMBL295725 | 0.77 | SHBG (0.44) | SHBGTP53KDM4EGMNNLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4197318-A | CYCLOHEXYL SUBSTITUTED ALKANOLS AS POTENTIATORS | JOHNSON & JOHNSON (US) | 1980-04-08 | — | — | US | claimed |
| US-4091090-A | PENETRANT ACCELERATOR COMPRISING CYCLOHEXYL-SUBSTITUTED ALKANOLS | JOHNSON & JOHNSON (US) | 1978-05-23 | — | — | US | claimed |
| US-4006218-A | MICROBIOCIDE | JOHNSON & JOHNSON (US) | 1977-02-01 | — | — | US | claimed |
| US-4474748-A | ANTIBIOTICS, FUNGICIDES, ANTISEPTICS | JOHNSON & JOHNSON (US) | 1984-10-02 | — | — | US | disclosed |
| US-4321257-A | Potentiated medicaments | JOHNSON & JOHNSON (US) | 1982-03-23 | — | — | US | disclosed |
| US-4197318-A | CYCLOHEXYL SUBSTITUTED ALKANOLS AS POTENTIATORS | JOHNSON & JOHNSON (US) | 1980-04-08 | — | — | US | disclosed |
| US-4091090-A | PENETRANT ACCELERATOR COMPRISING CYCLOHEXYL-SUBSTITUTED ALKANOLS | JOHNSON & JOHNSON (US) | 1978-05-23 | — | — | US | disclosed |
| US-4006218-A | MICROBIOCIDE | JOHNSON & JOHNSON (US) | 1977-02-01 | — | — | US | disclosed |