Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | MPI | P34949 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11098150 | 1.00 | ALDH1A1 (0.45) | ALDH1A1TSHRKDM4ELMNASMN1; SMN2 | |
| SCHEMBL6076526 | 0.81 | ALDH1A1 (0.46) | ALDH1A1TSHRKDM4ELMNASMN1; SMN2 | |
| SCHEMBL12763871 | 0.81 | ALDH1A1 (0.46) | ALDH1A1TSHRKDM4ELMNASMN1; SMN2 | |
| SCHEMBL6076524 | 0.81 | ALDH1A1 (0.46) | ALDH1A1TSHRKDM4ELMNASMN1; SMN2 | |
| SCHEMBL28618300 | 0.77 | ALDH1A1 (0.50) | ALDH1A1KDM4ELMNASMN1; SMN2MEN1 | |
| SCHEMBL13468052 | 0.76 | ALDH1A1 (0.42) | ALDH1A1TSHRKDM4ELMNASMN1; SMN2 | |
| SCHEMBL12764020 | 0.76 | SMN1; SMN2 (0.48) | ALDH1A1TSHRKDM4ELMNASMN1; SMN2 | |
| SCHEMBL28613057 | 0.75 | SMN1; SMN2 (0.41) | ALDH1A1LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL13044358 | 0.73 | ALDH1A1 (0.50) | ALDH1A1TSHRKDM4ELMNASMN1; SMN2 | |
| SCHEMBL16773866 | 0.73 | SMN1; SMN2 (0.40) | ALDH1A1TSHRKDM4ELMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0013111-B1 | 3'-(SUBSTITUTED PHENYL)-SPIRO(ISOBENZOFURAN-1(3H),5'(4'H)-ISOXAZOL)-3-ONES, PROCESS FOR THEIR PREPARATION, THEIR USE AS HERBICIDES AND PLANT GROWTH REGULANTS AND THEIR APPLICATION TO THE PREPARATION OF ISOXAZOLE DERIVATIVES | MONSANTO COMPANY (US) | 1984-02-22 | — | — | EP | disclosed |
| US-4401457-A | 3'-(Substituted phenyl)-spiro[isobenzofuran-1(3H),5'(4'H)-isoxazol]-3-ones and their use as herbicides | MONSANTO COMPANY (US) | 1983-08-30 | — | — | US | disclosed |
| US-4364768-A | FOR LEGUMES | MONSANTO COMPANY (US) | 1982-12-21 | — | — | US | disclosed |
| EP-0013111-A2 | 3'-(substituted phenyl)-spiro(isobenzofuran-1(3H),5'(4'H)-isoxazol)-3-ones, process for their preparation, their use as herbicides and plant growth regulants and their application to the preparation of isoxazole derivatives | MONSANTO COMPANY (US) | 1980-07-09 | — | — | EP | disclosed |
| US-4209629-A | HERBICIDES, PLANT GROWTH REGULATORS | MONSANTO COMPANY (US) | 1980-06-24 | — | — | US | disclosed |