SCHEMBL11098684

SCHEMBL11098684

O=P(Br)(Br)Oc1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SRC P12931 1/20 0.58
L3MBTL1 Q9Y468 2/20 0.56
TDP1 Q9NUW8 1/20 0.56
KDM4E B2RXH2 1/20 0.50
MEN1 O00255 4/20 0.45
KMT2A Q03164 4/20 0.45
HTT P42858 2/20 0.45
HPGD P15428 1/20 0.44
LMNA P02545 2/20 0.42
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
RECQL P46063 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
PKM P14618 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6932719 0.84 SRC (0.58) SRCL3MBTL1TDP1KDM4EMEN1
SCHEMBL19348680 0.80 SRC (0.54) SRCL3MBTL1TDP1KDM4EMEN1
SCHEMBL11105074 0.78 L3MBTL1 (0.61) SRCL3MBTL1TDP1KDM4EMEN1
SCHEMBL27771929 0.78 SRC (0.52) SRCL3MBTL1TDP1KDM4EMEN1
Triphenyl Phosphate SCHEMBL18116 0.78 SRC (0.64) SRCL3MBTL1TDP1KDM4EMEN1
Triphenyl Phosphate SCHEMBL28557783 0.78 SRC (0.64) SRCL3MBTL1TDP1KDM4EMEN1
Triphenyl Phosphate SCHEMBL483692 0.78 SRC (0.64) SRCL3MBTL1TDP1KDM4EMEN1
Triphenyl Phosphate SCHEMBL28761613 0.78 SRC (0.64) SRCL3MBTL1TDP1KDM4EMEN1
SCHEMBL28563480 0.78 SRC (0.64) SRCL3MBTL1TDP1KDM4EMEN1
SCHEMBL3961989 0.77 SRC (0.70) SRCL3MBTL1TDP1KDM4ECYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110746458-B Phosphorus-containing maleimide compound and preparation method thereof 南亚新材料科技股份有限公司 2022-01-11 CN claimed
CN-110746458-A Phosphorus-containing maleimide resin and preparation method thereof 南亚新材料科技股份有限公司 2020-02-04 CN claimed
EP-2768837-B1 NOVEL TETRAOXASPIRO[5.5]UNDECANE BASED PHOSPHATE COMPOUNDS AND THEIR USE AS FLAME RETARDANTS PERSTORP AB (SE) 2016-12-07 EP claimed
EP-2768837-A1 NOVEL TETRAOXASPIRO[5.5]UNDECANE BASED PHOSPHATE COMPOUNDS AND THEIR USE AS FLAME RETARDANTS PERSTORP AB (SE) 2014-08-27 EP claimed
WO-2013058690-A1 NOVEL TETRAOXASPIRO[5.5]UNDECANE BASED PHOSPHATE COMPOUNDS AND THEIR USE AS FLAME RETARDANTS PERSTORP AB (SE) 2013-04-25 WO claimed
US-4156663-A 260/857 R KANEBO, LTD. (JP) 1979-05-29 US claimed
US-4072658-A FLAME RETARDANTS KANEBO, LTD. (JA) 1978-02-07 US claimed
CN-110746458-B Phosphorus-containing maleimide compound and preparation method thereof 南亚新材料科技股份有限公司 2022-01-11 CN disclosed
CN-110746458-A Phosphorus-containing maleimide resin and preparation method thereof 南亚新材料科技股份有限公司 2020-02-04 CN disclosed
EP-2768837-B1 NOVEL TETRAOXASPIRO[5.5]UNDECANE BASED PHOSPHATE COMPOUNDS AND THEIR USE AS FLAME RETARDANTS PERSTORP AB (SE) 2016-12-07 EP disclosed
EP-2768837-A1 NOVEL TETRAOXASPIRO[5.5]UNDECANE BASED PHOSPHATE COMPOUNDS AND THEIR USE AS FLAME RETARDANTS PERSTORP AB (SE) 2014-08-27 EP disclosed
WO-2013058690-A1 NOVEL TETRAOXASPIRO[5.5]UNDECANE BASED PHOSPHATE COMPOUNDS AND THEIR USE AS FLAME RETARDANTS PERSTORP AB (SE) 2013-04-25 WO disclosed
CN-102796253-A ODOPB (10-(2,5-dihydroxyphenyl)-9,10-dihydro-9-oxa-10-phosphaphenanthrene-10-oxide)-base polyphosphate flame retardant, and preparation method and application thereof UNIV GUIZHOU NORMAL 2012-11-28 CN disclosed
EP-0019401-B1 PROCESS FOR PREPARING ENAMINE DERIVATIVES, COMPOUNDS SO PRODUCED AND PROCESS FOR PREPARING A 3-HYDROXY-CEPHALOSPORIN Lilly Industries Limited (GB) 1984-03-21 EP disclosed
US-4301280-A Preparation of 3-substituted cephalosporins LILLY INDUSTRIES LIMITED (GB) 1981-11-17 US disclosed
EP-0019401-A1 Process for preparing enamine derivatives, compounds so produced and process for preparing a 3-hydroxy-cephalosporin Lilly Industries Limited (GB) 1980-11-26 EP disclosed