Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 6/20 | 0.43 |
| ▸ | HTR2C | P28335 | 6/20 | 0.43 |
| ▸ | HRH1 | P35367 | 4/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.43 |
| ▸ | DRD2 | P14416 | 3/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.43 |
| ▸ | DRD1 | P21728 | 3/20 | 0.43 |
| ▸ | DRD3 | P35462 | 3/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL11263353 | 0.89 | HRH2 (0.52) | HTR2AHTR2CHRH1ADRA2ADRD2 | |
| Fumaric Acid SCHEMBL11101572 | 0.89 | HRH2 (0.52) | HTR2AHTR2CHRH1ADRA2ADRD2 | |
| SCHEMBL11098676 | 0.89 | HTR2A (0.40) | HTR2AHTR2CHRH1ADRA2ADRD2 | |
| SCHEMBL9434823 | 0.86 | HTR2A (0.46) | HTR2AHTR2CHRH1ADRA2ADRD2 | |
| SCHEMBL9433490 | 0.84 | HTR2A (0.44) | HTR2AHTR2CHRH1ADRA2ADRD2 | |
| SCHEMBL11101229 | 0.84 | LMNA (0.54) | HTR2AHTR2CHRH1LMNAMEN1 | |
| Fumaric Acid SCHEMBL11261237 | 0.80 | HRH2 (0.49) | HTR2AHTR2CHRH1ADRA2ADRD2 | |
| Fumaric Acid SCHEMBL11251972 | 0.80 | HRH2 (0.52) | HTR2AHTR2CHRH1ADRA2ADRD2 | |
| Fumaric Acid SCHEMBL11261244 | 0.80 | HRH2 (0.49) | HTR2AHTR2CHRH1ADRA2ADRD2 | |
| Fumaric Acid SCHEMBL11097331 | 0.80 | HRH2 (0.52) | HTR2AHTR2CHRH1ADRA2ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0035749-B1 | HETEROCYCLIC COMPOUNDS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | C.H. BOEHRINGER SOHN (DE) | 1984-06-06 | — | — | EP | disclosed |
| US-4313931-A | ANTIHISTAMINES, ANTISEROTONINE AGENTS, ANTIALLERGENS, BRONCHODILATOR AGENTS, ANTIANAPHYLACTIC AGENTS | BOEHRINGER INGELHEIM KG (DE) | 1982-02-02 | — | — | US | disclosed |