Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL845108 | 0.96 | TSHR (0.55) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL3502570 | 0.90 | TSHR (0.62) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL1270108 | 0.90 | TSHR (0.57) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL340893 | 0.88 | TSHR (0.54) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL12110929 | 0.88 | TSHR (0.50) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL15015550 | 0.87 | TSHR (0.49) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL16536218 | 0.86 | TSHR (0.51) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL16537187 | 0.85 | TSHR (0.60) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL11252984 | 0.85 | TSHR (0.51) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL29144983 | 0.85 | TSHR (0.44) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4432877-A | Organo-mercurial materials | NEW ENGLAND NUCLEAR CORPORATION (US) | 1984-02-21 | — | — | US | disclosed |