SCHEMBL340893

SCHEMBL340893

C=C(C)C(=O)OCCC[Si](CC)(OC)OC

nearest known ligand 0.54

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.54
THRB P10828 1/20 0.47
POLB P06746 1/20 0.39
APEX1 P27695 1/20 0.39
HTT P42858 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
ALDH1A1 P00352 3/20 0.36
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11252103 0.95 TSHR (0.57) TSHRTHRBPOLBAPEX1HTT
SCHEMBL16286966 0.94 TSHR (0.60) TSHRTHRBPOLBAPEX1HTT
SCHEMBL16536714 0.94 TSHR (0.60) TSHRTHRBPOLBAPEX1HTT
SCHEMBL845108 0.91 TSHR (0.55) TSHRTHRBPOLBAPEX1HTT
SCHEMBL339142 0.90 THRB (0.50) TSHRTHRBPOLBAPEX1HTT
SCHEMBL23002876 0.89 TSHR (0.44) TSHRTHRB
SCHEMBL3502570 0.89 TSHR (0.62) TSHRTHRBPOLBAPEX1HTT
SCHEMBL1270108 0.89 TSHR (0.57) TSHRTHRBPOLBAPEX1HTT
SCHEMBL11099142 0.88 TSHR (0.51) TSHRTHRBPOLBAPEX1HTT
SCHEMBL12110929 0.87 TSHR (0.50) TSHRTHRBPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 251 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119735813-A Tackifier, preparation method thereof and organic silicon optical cement 广东派乐玛新材料技术有限公司 2025-04-01 CN claimed
CN-112679679-B Polyphenyl silicon boron flame retardant containing sulfonic group and preparation method thereof 铨盛聚碳科技股份有限公司 2023-03-24 CN claimed
CN-112679679-A Polyphenyl silicon boron flame retardant containing sulfonic group and preparation method thereof 铨盛聚碳科技股份有限公司 2021-04-20 CN claimed
CN-108441056-B Environment-friendly fluorine circuit board conformal coating composition and preparation method and application thereof 太仓中化环保化工有限公司 2020-07-03 CN claimed
CN-110343251-A A kind of silicone photonic resin 深圳职业技术学院 2019-10-18 CN claimed
CN-106947031-B A kind of flucride siloxane fire retardant and the preparation method and application thereof 铨盛聚碳科技股份有限公司 2019-06-04 CN claimed
CN-108441056-A A kind of environment-friendly type fluorine element circuit board three proofings coating compositions and its preparation method and application 太仓中化环保化工有限公司 2018-08-24 CN claimed
US-9181458-B2 Method for manufacturing optical film-forming pressure-sensitive adhesive layer, optical film-forming pressure-sensitive adhesive layer, pressure-sensitive adhesive-type optical film, and image display device NITTO DENKO CORPORATION (JP) 2015-11-10 US claimed
US-12545747-B2 Method, kit, and device for preparing glycan from glycoprotein NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2026-02-10 US disclosed
US-20250389555-A1 MODIFIED HIGH-CIS POLYBUTADIENE POLYMER, RELATED METHODS AND RUBBER COMPOSITIONS BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2025-12-25 US disclosed
US-12410263-B2 Modified high-Cis polybutadiene polymer, related methods and rubber compositions BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2025-09-09 US disclosed
CN-119735813-A Tackifier, preparation method thereof and organic silicon optical cement 广东派乐玛新材料技术有限公司 2025-04-01 CN disclosed
US-20250066516-A1 HYDROGENATED POLYBUTADIENE POLYMERS AND RUBBER COMPOSITIONS INCORPORATING SAME BRIDGESTONE CORPORATION (JP) 2025-02-27 US disclosed
EP-4495146-A2 MODIFIED HIGH-CIS POLYBUTADIENE POLYMER, RELATED METHODS AND RUBBER COMPOSITIONS Bridgestone Americas Tire Operations, LLC (US) 2025-01-22 EP disclosed
US-5502107-A IMPACT STRENGTH DOW CORNING CORPORATION (US) 1996-03-26 US disclosed
EP-0696621-A1 COATING COMPOSITION AND SURFACE-COATED MOLDING PRODUCED THEREWITH MITSUBISHI RAYON CO., LTD. (JP) 1996-02-14 EP disclosed
EP-0691363-A1 Polystyrene modified with a telechelic polyorganosiloxane DOW CORNING CORPORATION (US) 1996-01-10 EP disclosed
US-4439557-A SILYL SUBSTITUTED ACRYLATES, CURING CATALYST TORAY INDUSTRIES, INCORPORATED (JP) 1984-03-27 US disclosed
EP-0065388-A1 Coating composition TORAY INDUSTRIES, INC. (JP) 1982-11-24 EP disclosed
US-4026826-A ALKOXYSILANES JAPAN ATOMIC ENERGY RESEARCH INSTITUTE (JA) 1977-05-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250389555-A1 MODIFIED HIGH-CIS POLYBUTADIENE POLYMER, RELATED METHODS AND RUBBER COMPOSITIONS MALT1, INO80C, RTCB TSHR 1694/4885THRB 529/4885POLB 298/4885
US-12545747-B2 Method, kit, and device for preparing glycan from glycoprotein FUT7, FUT4, SIGLEC7 TSHR 565/4885THRB 388/4885POLB 3362/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.