Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.57 |
| ▸ | THRB | P10828 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.50 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | RARB | P10826 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11099594 | 1.00 | MAPT (0.57) | MAPTTHRBSMN1; SMN2KMT2APLA2G1B | |
| SCHEMBL11307149 | 0.96 | MAPT (0.54) | MAPTTHRBSMN1; SMN2KMT2APLA2G1B | |
| SCHEMBL11554757 | 0.93 | MAPT (0.64) | MAPTTHRBSMN1; SMN2KMT2APLA2G1B | |
| SCHEMBL11556126 | 0.93 | MAPT (0.64) | MAPTTHRBSMN1; SMN2KMT2APLA2G1B | |
| SCHEMBL11100718 | 0.92 | RARB (0.56) | MAPTTHRBSMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL11101668 | 0.92 | RARB (0.56) | MAPTTHRBSMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL11222777 | 0.92 | RARB (0.56) | MAPTTHRBSMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL11097180 | 0.91 | MAPT (0.60) | MAPTTHRBSMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL11100407 | 0.91 | MAPT (0.60) | MAPTTHRBSMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL12736303 | 0.90 | MAPT (0.61) | MAPTTHRBSMN1; SMN2KMT2APLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4473487-A | 4-Fluorobiphenyl derivatives, their preparation, and dielectrics and electro-optical display element containing them | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1984-09-25 | — | — | US | disclosed |