Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL11441487 | 0.93 | TLR7 (0.47) | TLR7ALDH1A1NPC1KDM4ETP53 | |
| Propionic Acid SCHEMBL11443158 | 0.90 | TLR7 (0.44) | TLR7ALDH1A1NPC1KDM4ETLR8 | |
| SCHEMBL11184964 | 0.88 | TLR7 (0.51) | TLR7ALDH1A1NPC1KDM4ETP53 | |
| SCHEMBL9611690 | 0.88 | TLR7 (0.61) | TLR7ALDH1A1NPC1KDM4ETP53 | |
| SCHEMBL11448854 | 0.85 | TLR7 (0.49) | TLR7ALDH1A1NPC1KDM4ETP53 | |
| SCHEMBL11184987 | 0.85 | NPC1 (0.57) | TLR7ALDH1A1NPC1KDM4ETP53 | |
| SCHEMBL11434898 | 0.85 | TLR7 (0.49) | TLR7ALDH1A1NPC1KDM4ETP53 | |
| SCHEMBL16692216 | 0.85 | TLR7 (0.49) | TLR7ALDH1A1NPC1KDM4ETP53 | |
| SCHEMBL16692201 | 0.84 | TLR7 (0.48) | TLR7ALDH1A1NPC1KDM4ETP53 | |
| SCHEMBL16692144 | 0.84 | TLR7 (0.48) | TLR7ALDH1A1NPC1KDM4ETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435417-A | ANTIINFLAMMATORY AGENTS | GRUPPO LEPETIT S.P.A. (IT) | 1984-03-06 | — | — | US | disclosed |
| US-4389525-A | Process for the resolution of some interphenylene 9-thia-11-oxo-12-azaprostanoic acids | MERCK & CO., INC. (US) | 1983-06-21 | — | — | US | disclosed |
| EP-0012866-B1 | NEW 3H-NAPHTHO(1,2-D)IMIDAZOLES, PROCESSES FOR PREPARING THEM, COMPOUNDS FOR USE AS ANTIINFLAMMATORY AND ANTIMICROBIAL AGENTS AND COMPOSITIONS FOR THAT USE CONTAINING THEM | GRUPPO LEPETIT S.P.A. (IT) | 1983-01-19 | — | — | EP | disclosed |
| US-4340607-A | Antimicrobial 3H-naphtho[1,2-d]imidazoles | GRUPPO LEPETIT S.P.A. (IT) | 1982-07-20 | — | — | US | disclosed |
| EP-0012866-A1 | New 3H-naphtho(1,2-d)imidazoles, processes for preparing them, compounds for use as antiinflammatory and antimicrobial agents and compositions for that use containing them | GRUPPO LEPETIT S.P.A. (IT) | 1980-07-09 | — | — | EP | disclosed |