Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11184964 | 0.88 | TLR7 (0.51) | TLR7MEN1KMT2AMAPTKDM4E | |
| SCHEMBL9611690 | 0.88 | TLR7 (0.61) | TLR7MEN1KMT2ANR1H2NR1H3 | |
| SCHEMBL11287517 | 0.86 | HDAC3 (0.47) | TLR7MAPTKDM4ENPC1RAB9A | |
| SCHEMBL11448854 | 0.85 | TLR7 (0.49) | TLR7MEN1KMT2AMAPTKDM4E | |
| SCHEMBL16692216 | 0.85 | TLR7 (0.49) | TLR7MEN1KMT2AMAPTKDM4E | |
| SCHEMBL11184987 | 0.85 | NPC1 (0.57) | TLR7MEN1KMT2AMAPTKDM4E | |
| SCHEMBL11099196 | 0.85 | TLR7 (0.49) | TLR7MEN1KMT2AMAPTKDM4E | |
| SCHEMBL11449199 | 0.85 | TLR7 (0.46) | TLR7MEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL16692201 | 0.84 | TLR7 (0.48) | TLR7MEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL11079289 | 0.84 | TLR7 (0.51) | TLR7NR1H2NR1H3MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0012866-A1 | New 3H-naphtho(1,2-d)imidazoles, processes for preparing them, compounds for use as antiinflammatory and antimicrobial agents and compositions for that use containing them | GRUPPO LEPETIT S.P.A. (IT) | 1980-07-09 | — | — | EP | disclosed |