SCHEMBL11099221

SCHEMBL11099221

CCCCCC1COC(c2ccc(C(=O)Oc3ccc(C#N)c(Cl)c3)cc2)OC1

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.36
HPGD P15428 1/20 0.36
AR P10275 12/20 0.35
MRGPRX4 Q96LA9 1/20 0.35
PGR P06401 2/20 0.33
MAPT P10636 2/20 0.33
PRSS1 P07477 1/20 0.33
ACR P10323 1/20 0.33
NPC1 O15118 1/20 0.33
LMNA P02545 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9840026 0.89 ALDH1A1 (0.36) ALDH1A1HPGDMAPTPRSS1ACR
SCHEMBL10532006 0.89 ALDH1A1 (0.36) ALDH1A1HPGDMAPTPRSS1ACR
SCHEMBL10775955 0.88 ALDH1A1 (0.37) ALDH1A1HPGDMAPTPRSS1ACR
SCHEMBL10781664 0.88 ALDH1A1 (0.48) ALDH1A1HPGDNPC1LMNACYP1A2
SCHEMBL10778897 0.88 ALDH1A1 (0.37) ALDH1A1HPGDMAPTPRSS1ACR
SCHEMBL10777018 0.88 ALDH1A1 (0.37) ALDH1A1HPGDMAPTPRSS1ACR
SCHEMBL10776614 0.88 ALDH1A1 (0.37) ALDH1A1HPGDMAPTPRSS1ACR
SCHEMBL10775429 0.88 ALDH1A1 (0.37) ALDH1A1HPGDMAPTPRSS1ACR
SCHEMBL10776606 0.88 PRSS1 (0.37) ALDH1A1HPGDMAPTPRSS1ACR
SCHEMBL10781970 0.88 ALDH1A1 (0.50) ALDH1A1HPGDNPC1LMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4424371-A LIQUID CRYSTALS TIMEX CORPORATION (US) 1984-01-03 US disclosed