Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SCN1A | P35498 | 2/20 | 0.44 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.44 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.39 |
| ▸ | RARB | P10826 | 3/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11098131 | 1.00 | ALDH1A1 (0.45) | ALDH1A1HTTSCN1ASCN2ASCN3A | |
| SCHEMBL11102613 | 1.00 | ALDH1A1 (0.45) | ALDH1A1HTTSCN1ASCN2ASCN3A | |
| SCHEMBL11102882 | 0.99 | HTT (0.46) | ALDH1A1HTTSCN1ASCN2ASCN3A | |
| SCHEMBL11100553 | 0.95 | HTT (0.46) | ALDH1A1HTTSCN1ASCN2ASCN3A | |
| SCHEMBL11042489 | 0.91 | HTT (0.46) | ALDH1A1HTTSCN1ASCN2ASCN3A | |
| SCHEMBL11042479 | 0.91 | HTT (0.46) | ALDH1A1HTTSCN1ASCN2ASCN3A | |
| SCHEMBL11104527 | 0.90 | SCN1A (0.48) | ALDH1A1HTTSCN1ASCN2ASCN3A | |
| SCHEMBL28232676 | 0.89 | SCN1A (0.57) | ALDH1A1HTTSCN1ASCN2ASCN3A | |
| SCHEMBL9842645 | 0.89 | RARB (0.47) | ALDH1A1HTTSCN1ASCN2ASCN3A | |
| SCHEMBL9842724 | 0.88 | RARB (0.45) | ALDH1A1HTTSCN1ASCN2ASCN3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4473487-A | 4-Fluorobiphenyl derivatives, their preparation, and dielectrics and electro-optical display element containing them | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1984-09-25 | — | — | US | disclosed |