⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5532586 | 0.80 | CYP1A2 (0.37) | — | |
| SCHEMBL27172660 | 0.77 | CYP1A2 (0.47) | — | |
| SCHEMBL28598751 | 0.75 | — | — | |
| SCHEMBL9616911 | 0.75 | — | — | |
| SCHEMBL8226932 | 0.75 | — | — | |
| SCHEMBL8089593 | 0.75 | CYP1A2 (0.55) | — | |
| SCHEMBL19175448 | 0.74 | — | — | |
| SCHEMBL5709562 | 0.74 | — | — | |
| SCHEMBL19167324 | 0.74 | — | — | |
| SCHEMBL20976652 | 0.73 | MAOA (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117866177-A | Biodegradable full polyester nano particle and preparation method and application thereof | 复旦大学 | 2024-04-12 | — | — | CN | claimed |
| EP-0057360-B1 | CYCLIC CARBONIC ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS COPOLYMERISATION CONSTITUENTS FOR THE PREPARATION OF POLYCARBONATES | BAYER AG (DE) | 1984-09-26 | — | — | EP | claimed |
| CN-117866177-A | Biodegradable full polyester nano particle and preparation method and application thereof | 复旦大学 | 2024-04-12 | — | — | CN | disclosed |
| CN-115175952-B | Aqueous resin composition, aqueous paint and coated article | DIC株式会社 | 2023-08-29 | — | — | CN | disclosed |
| CN-116600834-A | Implant | 4D医学有限公司(以4D生物材料名义进行贸易) | 2023-08-15 | — | — | CN | disclosed |
| US-20230109243-A1 | AQUEOUS RESIN COMPOSITION, AQUEOUS PAINT, AND COATED ARTICLE | DIC CORPORATION (JP) | 2023-04-06 | — | — | US | disclosed |
| EP-4122974-A1 | AQUEOUS RESIN COMPOSITION, AQUEOUS COATING MATERIAL, AND COATED ARTICLE | DIC Corporation (JP) | 2023-01-25 | — | — | EP | disclosed |
| CN-115175952-A | Aqueous resin composition, aqueous coating material, and coated article | DIC株式会社 | 2022-10-11 | — | — | CN | disclosed |
| WO-2021241399-A1 | BLOCK COPOLYMER | 帝人株式会社 | 2021-12-02 | — | — | WO | disclosed |
| CN-107257813-B | Block copolymers having surface active anchoring groups, compositions and methods thereof | AZ电子材料卢森堡有限公司 | 2020-08-21 | — | — | CN | disclosed |
| EP-3259292-B1 | BLOCK COPOLYMERS WITH SURFACE-ACTIVE JUNCTION GROUPS, COMPOSITIONS AND PROCESSES THEREOF | AZ ELECTRONIC MAT LUXEMBOURG SARL (LU) | 2020-04-08 | — | — | EP | disclosed |
| US-20130281475-A1 | INHIBITORS OF C-FMS KINASE | JANSSEN PHARMACEUTICA NV (BE) | 2013-10-24 | — | — | US | disclosed |
| US-20110195960-A1 | INHIBITORS OF C-FMS KINASE | ILLIG CARL R | 2011-08-11 | — | — | US | disclosed |
| US-7973035-B2 | Inhibitors of C-FMS kinase | JANSSEN PHARMACEUTICA, N.V. (BE) | 2011-07-05 | — | — | US | disclosed |
| US-20080275031-A1 | 4-Cyano-1H-imidazole-2-carboxylic acid [2-cyclohex-1-enyl-4-(2,6-dioxo-piperidin-4-yl)-phenyl]-amide; tyrosine kinase inhibitor; autoimmune diseases, antiinflammatory, anticarcinogenic agent | ILLIG CARL R | 2008-11-06 | — | — | US | disclosed |
| US-7414050-B2 | e.g. 4-Cyano-1H-imidazole-2-carboxylic acid [2-cyclohex-1-enyl-4-(2,6-dioxo-piperidin-4-yl)-phenyl]-amide; tyrosine kinase inhibitor; autoimmune diseases, antiinflammatory, anticarcinogenic agent | JANSSEN PHARMACEUTICA, N.V. (BE) | 2008-08-19 | — | — | US | disclosed |
| US-20070249593-A1 | e.g. 4-Cyano-1H-imidazole-2-carboxylic acid [2-cyclohex-1-enyl-4-(2,6-dioxo-piperidin-4-yl)-phenyl]-amide; tyrosine kinase inhibitor; autoimmune diseases, antiinflammatory, anticarcinogenic agent | JANSSEN PHARMACEUTICA, N.V. (BE) | 2007-10-25 | — | — | US | disclosed |
| EP-0057360-B1 | CYCLIC CARBONIC ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS COPOLYMERISATION CONSTITUENTS FOR THE PREPARATION OF POLYCARBONATES | BAYER AG (DE) | 1984-09-26 | — | — | EP | disclosed |
| US-4177342-A | FROM CARBAMATE(URETHANE)-CONTAINING ALCOHOLS AND POLYISOCYANATES | BAYER AKTIENGESELLSCHAFT (DE) | 1979-12-04 | — | — | US | disclosed |
| EP-0000016-A1 | Process for the preparation of allophanates-substituted polyisocyanates and their use in the manufacture of polyurethane products | BAYER AG (DE) | 1978-12-20 | — | — | EP | disclosed |