Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.63 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.49 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | PRKDC | P78527 | 1/20 | 0.46 |
| ▸ | NPY1R | P25929 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11835196 | 0.86 | PTGER1 (0.45) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| Hydrochloric Acid SCHEMBL11102989 | 0.85 | KMT2A (0.55) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| SCHEMBL9537786 | 0.84 | KMT2A (0.81) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| SCHEMBL9537746 | 0.82 | KMT2A (0.79) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| SCHEMBL312287 | 0.82 | KMT2A (0.92) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| SCHEMBL5924878 | 0.82 | F2RL3 (0.53) | KMT2ALMNAALDH1A1MAPTHPGD | |
| SCHEMBL10916834 | 0.81 | KMT2A (0.76) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| SCHEMBL2705832 | 0.81 | KMT2A (0.76) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| SCHEMBL6393682 | 0.80 | LMNA (0.90) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| SCHEMBL10611772 | 0.80 | KMT2A (0.73) | KMT2ATDP1SLC6A2SLC6A3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0057141-B1 | ESTERS OF HALOGENE-BIPHENYLCARBOXYLATES, METHOD OF PREPARATION AND THEIR APPLICATION AS MEDICINES | PIERRE FABRE S.A. (FR) | 1984-04-04 | — | — | EP | claimed |