Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMOX1 | P09601 | 1/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.45 |
| ▸ | NMT1 | P30419 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11101069 | 0.99 | HMOX1 (0.55) | HMOX1CYP19A1TBXAS1 | |
| SCHEMBL11103538 | 0.95 | CYP19A1 (0.54) | HMOX1CYP19A1TBXAS1 | |
| SCHEMBL11101855 | 0.83 | CYP11B1 (0.55) | CYP19A1TBXAS1 | |
| SCHEMBL12045347 | 0.78 | HMOX1 (0.84) | HMOX1CYP19A1TBXAS1 | |
| SCHEMBL10923779 | 0.77 | PDE3B (0.56) | HMOX1CYP19A1TBXAS1 | |
| SCHEMBL10925624 | 0.77 | PDE3B (0.56) | HMOX1CYP19A1TBXAS1 | |
| SCHEMBL10927060 | 0.77 | PDE3B (0.56) | HMOX1CYP19A1TBXAS1 | |
| SCHEMBL10925604 | 0.77 | PDE3B (0.56) | HMOX1CYP19A1TBXAS1 | |
| SCHEMBL10927357 | 0.77 | PDE3B (0.56) | HMOX1CYP19A1TBXAS1 | |
| SCHEMBL10923822 | 0.77 | PDE3B (0.56) | HMOX1CYP19A1TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0122419-A2 | Substituted 3-mercaptopyridazines, their 3-alkylthio derivatives and processes for their preparation | A. Nattermann & Cie. GmbH (DE) | 1984-10-24 | — | — | EP | disclosed |