Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.69 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11072972 | 0.91 | MAPT (0.66) | MAPTPPARGCYP24A1CYP19A1HSP90AA1 | |
| SCHEMBL11098305 | 0.89 | MAPT (0.54) | MAPTPPARGCYP19A1MEN1KMT2A | |
| SCHEMBL11097860 | 0.89 | MAPT (0.54) | MAPTPPARGCYP19A1HSP90AA1MEN1 | |
| SCHEMBL11081070 | 0.86 | MAPT (0.76) | MAPTPPARGCYP24A1CYP19A1HSP90AA1 | |
| SCHEMBL9824981 | 0.82 | MAPT (1.00) | MAPTPPARGCYP24A1CYP19A1HSP90AA1 | |
| SCHEMBL11129336 | 0.81 | MAPT (0.52) | MAPTPPARGCYP19A1HSP90AA1MEN1 | |
| SCHEMBL11076481 | 0.81 | MAPT (0.52) | MAPTPPARGCYP19A1MEN1KMT2A | |
| SCHEMBL11099560 | 0.80 | CYP24A1 (0.64) | MAPTCYP24A1CYP19A1 | |
| SCHEMBL10727541 | 0.79 | MAPT (0.79) | MAPTPPARGCYP24A1CYP19A1HSP90AA1 | |
| SCHEMBL10849731 | 0.78 | MAPT (0.77) | MAPTPPARGCYP24A1CYP19A1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0125409-A2 | 4-Azolyl-pentanenitriles, process for their preparation and biocides containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1984-11-21 | — | — | EP | claimed |
| EP-0125409-A2 | 4-Azolyl-pentanenitriles, process for their preparation and biocides containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1984-11-21 | — | — | EP | disclosed |