SCHEMBL11099560

SCHEMBL11099560

CCC(C#N)(CC)C(=O)C(Cc1ccccc1)n1ccnc1

nearest known ligand 0.64

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CYP24A1 Q07973 1/20 0.64
TBXA2R P21731 16/20 0.48
CYP19A1 P11511 1/20 0.43
MAPT P10636 1/20 0.42
CYP17A1 P05093 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11068105 0.91 CYP24A1 (0.61) CYP24A1TBXA2RCYP19A1MAPTCYP17A1
SCHEMBL11078658 0.81 CYP24A1 (0.51) CYP24A1TBXA2RCYP19A1CYP17A1
SCHEMBL11099667 0.80 MAPT (0.69) CYP24A1CYP19A1MAPT
SCHEMBL6201802 0.76 CYP24A1 (0.62) CYP24A1TBXA2RCYP19A1CYP17A1
SCHEMBL11073325 0.75 CYP24A1 (0.57) CYP24A1TBXA2RCYP19A1
SCHEMBL3945738 0.75 CYP24A1 (0.63) CYP24A1TBXA2RCYP19A1CYP17A1
SCHEMBL27721148 0.73 CYP24A1 (0.64) CYP24A1TBXA2RCYP19A1MAPT
SCHEMBL6318924 0.71 TBXA2R (0.57) CYP24A1TBXA2RCYP19A1
SCHEMBL11072972 0.71 MAPT (0.66) CYP24A1CYP19A1MAPT
Trifluoromethanesulfonic Acid SCHEMBL28834589 0.71 CYP24A1 (0.58) CYP24A1TBXA2RCYP19A1CYP17A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0125409-A2 4-Azolyl-pentanenitriles, process for their preparation and biocides containing them SCHERING AKTIENGESELLSCHAFT (DE) 1984-11-21 EP claimed
EP-0125409-A2 4-Azolyl-pentanenitriles, process for their preparation and biocides containing them SCHERING AKTIENGESELLSCHAFT (DE) 1984-11-21 EP disclosed