Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | CASR | P41180 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4350908 | 0.82 | GAA (0.47) | GAAALDH1A1KMT2AMEN1HTT | |
| SCHEMBL4340530 | 0.80 | GAA (0.45) | GAAALDH1A1KMT2AMEN1HTT | |
| SCHEMBL294227 | 0.79 | CA1 (0.43) | GAAALDH1A1CA1CA2CA12 | |
| SCHEMBL294805 | 0.79 | CA1 (0.43) | GAAALDH1A1CA1CA2CA12 | |
| SCHEMBL4334371 | 0.79 | GAA (0.47) | GAAALDH1A1KMT2AMEN1CASR | |
| SCHEMBL294274 | 0.76 | CA1 (0.40) | GAAALDH1A1CA1CA2CA12 | |
| SCHEMBL1153615 | 0.76 | CA1 (0.40) | GAAALDH1A1CA1CA2CA12 | |
| SCHEMBL1153785 | 0.75 | GAA (0.41) | GAAALDH1A1KMT2AMEN1HTT | |
| SCHEMBL1153935 | 0.73 | L3MBTL1 (0.43) | GAAALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL1154023 | 0.73 | L3MBTL1 (0.41) | GAAALDH1A1KMT2AMEN1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0044158-A1 | Novel optically active imidazolidin-2-one derivatives and their production | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-01-20 | — | — | EP | claimed |
| EP-0044158-B1 | NOVEL OPTICALLY ACTIVE IMIDAZOLIDIN-2-ONE DERIVATIVES AND THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-08-15 | — | — | EP | disclosed |
| US-4403096-A | Optically active imidazolidin-2-one derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-09-06 | — | — | US | disclosed |
| EP-0075868-A2 | Optically active amino alcohols and their production | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-04-06 | — | — | EP | disclosed |
| EP-0044158-A1 | Novel optically active imidazolidin-2-one derivatives and their production | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-01-20 | — | — | EP | disclosed |