Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | CDK1 | P06493 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11100011 | 0.93 | GAA (0.55) | GAACDK1ALDH1A1MAPTCYP1A2 | |
| SCHEMBL11100645 | 0.92 | GAA (0.44) | GAACDK1ALDH1A1LMNAMAPT | |
| SCHEMBL11100056 | 0.92 | GAA (0.48) | GAACDK1TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL10498570 | 0.89 | GAA (0.40) | GAACDK1TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL10498343 | 0.86 | GAA (0.50) | GAACDK1ALDH1A1MAPTCYP1A2 | |
| SCHEMBL11100017 | 0.84 | GAA (0.55) | GAACDK1TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL11104340 | 0.84 | GAA (0.38) | GAACDK1ALDH1A1MAPT | |
| SCHEMBL9419172 | 0.84 | GAA (0.52) | GAACDK1TSHRSMN1; SMN2MAPT | |
| SCHEMBL9662388 | 0.83 | GAA (0.47) | GAACDK1TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL11101777 | 0.83 | GAA (0.40) | GAACDK1SMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0030142-B1 | HERBICIDAL UREAS, PREPARATION, COMPOSITIONS AND USE THEREOF | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-12-05 | — | — | EP | claimed |
| EP-0030142-A2 | Herbicidal ureas, preparation, compositions and use thereof | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-06-10 | — | — | EP | claimed |
| EP-0030142-B1 | HERBICIDAL UREAS, PREPARATION, COMPOSITIONS AND USE THEREOF | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-12-05 | — | — | EP | disclosed |
| EP-0030142-A2 | Herbicidal ureas, preparation, compositions and use thereof | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-06-10 | — | — | EP | disclosed |