Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | GMNN | O75496 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.47 |
| ▸ | BLM | P54132 | 2/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | PRKCA | P17252 | 1/20 | 0.47 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.47 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.47 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11100702 | 0.98 | MAPK1 (0.55) | MAPK1MAPTLMNAALDH1A1CYP1A2 | |
| SCHEMBL10800244 | 0.98 | MAPK1 (0.55) | MAPK1MAPTLMNAALDH1A1CYP1A2 | |
| SCHEMBL11105366 | 0.98 | MAPK1 (0.55) | MAPK1MAPTLMNAALDH1A1CYP1A2 | |
| SCHEMBL10802862 | 0.91 | PRKCA (0.55) | MAPK1MAPTLMNAALDH1A1PRKCA | |
| SCHEMBL10804978 | 0.91 | PRKCA (0.55) | MAPK1MAPTLMNAALDH1A1PRKCA | |
| SCHEMBL9743364 | 0.89 | MAPK1 (0.54) | MAPK1MAPTLMNAALDH1A1CYP1A2 | |
| SCHEMBL9745613 | 0.89 | MAPK1 (0.54) | MAPK1MAPTLMNAALDH1A1CYP1A2 | |
| SCHEMBL9743373 | 0.88 | MAPK1 (0.57) | MAPK1MAPTLMNAALDH1A1CYP1A2 | |
| SCHEMBL9743620 | 0.88 | MAPK1 (0.57) | MAPK1MAPTLMNAALDH1A1CYP1A2 | |
| SCHEMBL9742357 | 0.88 | MAPK1 (0.57) | MAPK1MAPTLMNAALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4436726-A | TREATMENT OF IMMUNE DEFICIENCY DISEASES AND THROMBOSIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-03-13 | — | — | US | disclosed |
| EP-0054435-B1 | N-ACYL PEPTIDE COMPOUNDS, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-01-25 | — | — | EP | disclosed |
| EP-0054435-A1 | N-acyl peptide compounds, processes for the preparation thereof and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-06-23 | — | — | EP | disclosed |