⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3688612 | 0.71 | — | — | |
| SCHEMBL628404 | 0.67 | — | — | |
| SCHEMBL4926015 | 0.67 | — | — | |
| SCHEMBL4927778 | 0.67 | — | — | |
| SCHEMBL30462530 | 0.67 | GABRP (0.40) | — | |
| SCHEMBL14958469 | 0.60 | — | — | |
| SCHEMBL27380013 | 0.59 | — | — | |
| SCHEMBL30441905 | 0.59 | — | — | |
| SCHEMBL28198710 | 0.59 | — | — | |
| SCHEMBL27451482 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1034571-C | A method for producing a pyrrolidire derivative | SHIONOGI & CO (JP) | 1997-04-16 | — | — | CN | disclosed |
| CN-1032257-C | Process for producing pyrrolidinethinyl carbapenem derivatives | SHIONOGI SEIYAKU KK (JP) | 1996-07-10 | — | — | CN | disclosed |
| CN-1113233-A | A method for producing a pyrrolidire derivative | SHIONOGI & CO (JP) | 1995-12-13 | — | — | CN | disclosed |
| CN-1071428-A | Pyrrolidinylthiocarbapenem derivatives | SHIONOGI & CO (JP) | 1993-04-28 | — | — | CN | disclosed |
| EP-0126587-A1 | Carboxylic thio-pyrrolidinyl beta-lactam compounds and production thereof | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1984-11-28 | — | — | EP | disclosed |