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Tyrosine

Tyrosine

SCHEMBL11101797

C[C@@H](OC(=O)[C@@H](N)CCCNC(=N)N)[C@H](N)C(=O)O.N[C@@H](Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.51

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 15/20 0.51
▸ NPY1R P25929 9/20 0.51
▸ NPY5R Q15761 7/20 0.49
▸ NPY2R P49146 5/20 0.49
▸ SLC7A5 Q01650 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tyrosine SCHEMBL11412240 0.89 NPY4R (0.45) NPY4RNPY1RNPY5RNPY2RSLC7A5
Tyrosine SCHEMBL6368324 0.88 NPY4R (0.58) NPY4RNPY1RNPY5RNPY2RSLC7A5
Tyrosine SCHEMBL11416635 0.87 NPY4R (0.45) NPY4RNPY1RNPY5RNPY2RSLC7A5
Tyrosine SCHEMBL27138396 0.87 NPY4R (0.53) NPY4RNPY1RNPY5RNPY2RSLC7A5
Tyrosine SCHEMBL28440222 0.85 SLC7A5 (0.56) NPY4RNPY1RNPY5RNPY2RSLC7A5
Tyrosine SCHEMBL29245680 0.85 SLC7A5 (0.58) NPY4RNPY1RNPY5RNPY2RSLC7A5
Tyrosine SCHEMBL1551967 0.85 SLC7A5 (0.61) NPY4RNPY1RNPY5RNPY2RSLC7A5
Arginine SCHEMBL904454 0.85 OTC (0.41) NPY4RNPY1RNPY5RNPY2R
SCHEMBL1965668 0.85 NPY4R (0.38) NPY4RNPY1RNPY5RNPY2R
Tyrosine SCHEMBL27546004 0.84 NPY4R (0.51) NPY4RNPY1RNPY5RNPY2RSLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4455290-A ANTICOAGULANTS RESEARCH CORPORATION (US) 1984-06-19 — — US disclosed