Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 11/20 | 0.53 |
| ▸ | FAAH | O00519 | 4/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 2/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HPN | P05981 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10613658 | 0.90 | ESR1 (0.51) | MGLLFAAHHSP90AA1PKMALDH1A1 | |
| SCHEMBL1156245 | 0.87 | MGLL (0.60) | MGLLFAAHHSP90AA1PKMALDH1A1 | |
| SCHEMBL27491984 | 0.82 | MGLL (0.72) | MGLLFAAHHSP90AA1PKMALDH1A1 | |
| SCHEMBL29510527 | 0.82 | MGLL (0.72) | MGLLFAAHHSP90AA1PKMALDH1A1 | |
| SCHEMBL139055 | 0.82 | MGLL (0.72) | MGLLFAAHHSP90AA1PKMALDH1A1 | |
| SCHEMBL28029842 | 0.81 | MGLL (0.51) | MGLLFAAHHSP90AA1PKMALDH1A1 | |
| SCHEMBL28385993 | 0.80 | MGLL (0.64) | MGLLFAAHHSP90AA1PKMALDH1A1 | |
| SCHEMBL1492513 | 0.78 | ESR1 (0.68) | ALDH1A1ESR1ESR2TDP1 | |
| SCHEMBL31284901 | 0.78 | ESR1 (0.68) | ALDH1A1ESR1ESR2TDP1 | |
| SCHEMBL5145523 | 0.78 | MGLL (0.52) | MGLLFAAHHSP90AA1PKMESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0051687-B1 | MALEIMIDES AND PROCESS FOR THE PREPARATION OF SAME | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1984-05-16 | — | — | EP | disclosed |
| US-4400521-A | RESINS, VARNICHES, CURING AGENTS, LAMINATION, ADHESIVES, HEAT RESISTANCE | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1983-08-23 | — | — | US | disclosed |
| EP-0051687-A1 | Maleimides and process for the preparation of same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1982-05-19 | — | — | EP | disclosed |