Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GUSB | P08236 | 1/20 | 0.38 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11101128 | 1.00 | HTR2C (0.49) | HTR2CKDM4EALDH1A1HPGDHTR2A | |
| Fumaric Acid SCHEMBL11106117 | 0.90 | HTR2C (0.42) | HTR2CKDM4EALDH1A1HPGDHTR2A | |
| Maleic Acid SCHEMBL11106110 | 0.90 | HTR2C (0.42) | HTR2CKDM4EALDH1A1HPGDHTR2A | |
| SCHEMBL11106652 | 0.90 | HRH1 (0.51) | HTR2CKDM4EALDH1A1HPGDHTR2A | |
| SCHEMBL11104195 | 0.90 | HRH1 (0.51) | HTR2CKDM4EALDH1A1HPGDHTR2A | |
| SCHEMBL11102181 | 0.85 | HTR2C (0.55) | HTR2CKDM4EALDH1A1HPGDHTR2A | |
| SCHEMBL11103525 | 0.82 | ALDH1A1 (0.40) | HTR2CKDM4EALDH1A1HPGDSMN1; SMN2 | |
| Fumaric Acid SCHEMBL11104211 | 0.80 | HRH1 (0.41) | HTR2CKDM4EALDH1A1HTR2AHRH1 | |
| Maleic Acid SCHEMBL11104208 | 0.80 | HRH1 (0.41) | HTR2CKDM4EALDH1A1HTR2AHRH1 | |
| SCHEMBL11281402 | 0.79 | HTR2C (0.67) | HTR2CKDM4EALDH1A1HPGDHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435566-A | HYPOGLYCEMIA, ANTIHISTAMINE, ANTIDIABETIC ACTIVITY | MARUKO SEIYAKU CO., LTD. (JP) | 1984-03-06 | — | — | US | claimed |
| US-4435566-A | HYPOGLYCEMIA, ANTIHISTAMINE, ANTIDIABETIC ACTIVITY | MARUKO SEIYAKU CO., LTD. (JP) | 1984-03-06 | — | — | US | disclosed |