Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.44 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11286500 | 0.90 | KDM4E (0.45) | KDM4ETP53ALOX15PIK3CDPIK3R1 | |
| SCHEMBL11105619 | 0.90 | KDM4E (0.45) | KDM4ETP53ALOX15PIK3CDPIK3R1 | |
| SCHEMBL11110999 | 0.88 | KDM4E (0.46) | KDM4ETP53ALOX15PIK3CDPIK3R1 | |
| SCHEMBL11103158 | 0.87 | SMN1; SMN2 (0.45) | KDM4EALDH1A1MEN1KMT2AHTT | |
| SCHEMBL11107956 | 0.84 | PDE5A (0.37) | KDM4EALOX15ALDH1A1MEN1KMT2A | |
| SCHEMBL11289842 | 0.82 | KDM4E (0.43) | KDM4ETP53ALOX15PIK3CDPIK3R1 | |
| SCHEMBL11109862 | 0.82 | SMN1; SMN2 (0.38) | KDM4EALOX15ALDH1A1HTTHPGD | |
| SCHEMBL11107454 | 0.81 | SMN1; SMN2 (0.40) | KDM4ETP53ALDH1A1MEN1KMT2A | |
| SCHEMBL11109252 | 0.81 | DRD2 (0.47) | KDM4EALOX15ALDH1A1MEN1KMT2A | |
| SCHEMBL11249955 | 0.81 | PIK3CD (0.61) | KDM4EALOX15PIK3CDPIK3R1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435402-A | Aminopyrimidine derivatives, processes for their preparation, and fungicidal, insecticidal and acaricidal compositions containing them | SANKYO COMPANY, LIMITED (JP) | 1984-03-06 | — | — | US | disclosed |
| EP-0057440-A1 | Aminopyrimidine derivatives, processes for their preparation, and fungicidal, insecticidal and acaricidal compositions containing them | SANKYO COMPANY LIMITED (JP) | 1982-08-11 | — | — | EP | disclosed |