Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR3 | O60755 | 2/20 | 0.40 |
| ▸ | PDE5A | O76074 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.35 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11110174 | 0.91 | GALR3 (0.41) | GALR3PDE5ARAB9ASMN1; SMN2MEN1 | |
| SCHEMBL11106244 | 0.91 | GALR3 (0.40) | GALR3PDE5ARAB9ASMN1; SMN2PIK3CD | |
| SCHEMBL11107956 | 0.88 | PDE5A (0.37) | GALR3PDE5ARAB9ASMN1; SMN2MEN1 | |
| SCHEMBL11034640 | 0.88 | S1PR2 (0.40) | GALR3SMN1; SMN2MEN1MAPK1STAT3 | |
| SCHEMBL11110500 | 0.87 | S1PR2 (0.41) | GALR3SMN1; SMN2MEN1MAPK1STAT3 | |
| SCHEMBL11107134 | 0.87 | S1PR2 (0.41) | GALR3SMN1; SMN2MEN1MAPK1STAT3 | |
| SCHEMBL11111531 | 0.87 | S1PR2 (0.41) | GALR3SMN1; SMN2MEN1MAPK1STAT3 | |
| SCHEMBL11286500 | 0.86 | KDM4E (0.45) | RAB9ASMN1; SMN2PIK3CDPIK3R1MEN1 | |
| SCHEMBL11111880 | 0.86 | SMN1; SMN2 (0.43) | GALR3RAB9ASMN1; SMN2PIK3CDPIK3R1 | |
| SCHEMBL11105399 | 0.86 | MAPT (0.39) | GALR3SMN1; SMN2MEN1MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435402-A | Aminopyrimidine derivatives, processes for their preparation, and fungicidal, insecticidal and acaricidal compositions containing them | SANKYO COMPANY, LIMITED (JP) | 1984-03-06 | — | — | US | disclosed |
| EP-0057440-A1 | Aminopyrimidine derivatives, processes for their preparation, and fungicidal, insecticidal and acaricidal compositions containing them | SANKYO COMPANY LIMITED (JP) | 1982-08-11 | — | — | EP | disclosed |