Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Nitric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.36 |
| ▸ | FDPS | P14324 | 9/20 | 0.35 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.34 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitric Acid SCHEMBL10869631 | 0.87 | ALDH1A1 (0.41) | ALDH1A1GGPS1FDPSSMPD1CES2 | |
| Nitric Acid SCHEMBL10869666 | 0.87 | ALDH1A1 (0.41) | ALDH1A1GGPS1FDPSSMPD1CES2 | |
| Nitric Acid SCHEMBL11101822 | 0.86 | ALDH1A1 (0.39) | ALDH1A1GGPS1FDPSSMPD1CES2 | |
| Nitric Acid SCHEMBL11103389 | 0.84 | ALDH1A1 (0.38) | ALDH1A1GGPS1FDPSSMPD1CES2 | |
| SCHEMBL1117372 | 0.83 | ALDH1A1 (0.43) | ALDH1A1GGPS1FDPSSMPD1CES2 | |
| SCHEMBL1117456 | 0.83 | ALDH1A1 (0.43) | ALDH1A1GGPS1FDPSSMPD1CES2 | |
| SCHEMBL1117460 | 0.83 | ALDH1A1 (0.43) | ALDH1A1GGPS1FDPSSMPD1CES2 | |
| SCHEMBL1170931 | 0.83 | ALDH1A1 (0.43) | ALDH1A1GGPS1FDPSSMPD1CES2 | |
| SCHEMBL1117922 | 0.83 | ALDH1A1 (0.43) | ALDH1A1GGPS1FDPSSMPD1CES2 | |
| SCHEMBL1170680 | 0.83 | ALDH1A1 (0.43) | ALDH1A1GGPS1FDPSSMPD1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0101093-A2 | Diesel fuel composition | ETHYL CORPORATION (US) | 1984-02-22 | — | — | EP | disclosed |
| US-4417903-A | NITRO-ALKYLNITRATE ESTER ANTIKNOCK ADDITIVES | ETHYL CORPORATION (US) | 1983-11-29 | — | — | US | disclosed |