Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11105075 | 1.00 | KMT2A (0.47) | KMT2ASMN1; SMN2TDP1HTTELANE | |
| SCHEMBL11102589 | 0.91 | KMT2A (0.44) | KMT2ASMN1; SMN2TDP1HTTELANE | |
| SCHEMBL11102586 | 0.91 | KMT2A (0.44) | KMT2ASMN1; SMN2TDP1HTTELANE | |
| SCHEMBL11100906 | 0.90 | FAAH (0.43) | KMT2ASMN1; SMN2TDP1HTTELANE | |
| SCHEMBL11100904 | 0.90 | FAAH (0.43) | KMT2ASMN1; SMN2TDP1HTTELANE | |
| SCHEMBL11102984 | 0.88 | SMN1; SMN2 (0.46) | KMT2ASMN1; SMN2TDP1HTTELANE | |
| SCHEMBL11102981 | 0.88 | SMN1; SMN2 (0.46) | KMT2ASMN1; SMN2TDP1HTTELANE | |
| SCHEMBL11110294 | 0.88 | FAAH (0.42) | KMT2ASMN1; SMN2TDP1HTTELANE | |
| SCHEMBL11110290 | 0.88 | FAAH (0.42) | KMT2ASMN1; SMN2TDP1HTTELANE | |
| SCHEMBL9842435 | 0.87 | APP (0.40) | KMT2ASMN1; SMN2TDP1HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4473487-A | 4-Fluorobiphenyl derivatives, their preparation, and dielectrics and electro-optical display element containing them | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1984-09-25 | — | — | US | disclosed |