Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.42 |
| ▸ | PPIA | P62937 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11109275 | 0.89 | MEN1 (0.42) | ATMMEN1KMT2APTGDR2PPIA | |
| SCHEMBL11105058 | 0.84 | CYP1A2 (0.42) | ATMMEN1KMT2APTGDR2PPIA | |
| SCHEMBL11110129 | 0.83 | APEX1 (0.47) | APEX1ATMPPIA | |
| SCHEMBL11113459 | 0.81 | APEX1 (0.51) | APEX1ATMMEN1KMT2ACYP2C9 | |
| SCHEMBL11111155 | 0.81 | APEX1 (0.47) | APEX1ATMPTGDR2 | |
| Hydrochloric Acid SCHEMBL11108436 | 0.81 | CYP1A2 (0.39) | ATMMEN1KMT2APPIACYP2C9 | |
| SCHEMBL11109355 | 0.81 | MEN1 (0.43) | ATMMEN1KMT2APTGDR2PPIA | |
| SCHEMBL11108113 | 0.78 | POLB (0.39) | MEN1KMT2APTGDR2CYP2C9CYP1A2 | |
| SCHEMBL11101143 | 0.78 | PPIA (0.42) | ATMMEN1KMT2APTGDR2PPIA | |
| SCHEMBL11107174 | 0.78 | ATM (0.69) | APEX1ATMMEN1KMT2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4463001-A | ANTIULCER AGENTS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1984-07-31 | — | — | US | disclosed |