Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PPIA | P62937 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11108602 | 0.87 | KDM4E (0.39) | AKR1B1KDM4EPPIACYP19A1 | |
| SCHEMBL11108077 | 0.86 | APEX1 (0.50) | APEX1ATMAKR1B1TSHRKDM4E | |
| SCHEMBL11113459 | 0.84 | APEX1 (0.51) | APEX1ATMALDH1A1HSD17B10TSHR | |
| SCHEMBL11111155 | 0.84 | APEX1 (0.47) | APEX1ATMALDH1A1HSD17B10 | |
| SCHEMBL11106295 | 0.83 | APEX1 (0.43) | APEX1ATMPPIA | |
| SCHEMBL11101724 | 0.83 | CYP1A2 (0.44) | ALDH1A1TSHRKDM4ELMNA | |
| SCHEMBL11107174 | 0.81 | ATM (0.69) | APEX1ATMALDH1A1HSD17B10TSHR | |
| SCHEMBL11106968 | 0.80 | HTR2C (0.41) | ALDH1A1SMN1; SMN2CYP19A1 | |
| SCHEMBL11106265 | 0.80 | CYP1A2 (0.44) | APEX1ATMAKR1B1ALDH1A1TSHR | |
| SCHEMBL11108437 | 0.79 | PPIA (0.39) | AKR1B1ALDH1A1PPIACYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4463001-A | ANTIULCER AGENTS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1984-07-31 | — | — | US | disclosed |